Metal-free synthesis of benzimidazo[2,1-a]ellipticines via tandem inter and intramolecular cyclization

被引：17

作者：

Chaitanya, T. Krishna ^{[1
]}

Prakash, K. S. ^{[1
]}

Nagarajan, Rajagopal ^{[1
]}

机构：

[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India

来源：

TETRAHEDRON | 2011年 / 67卷 / 36期

关键词：

Metal-free synthesis; Benzimidazo[2,1-a]ellipticine derivatives; 5-endo; 6-endo Cyclization; 1,2-Aryldiamines; Tandem cyclization; BIOLOGICAL EVALUATION; CALOTHRIXIN-A; ELLIPTICINE; ALKALOIDS; ISOQUINOLINES; BENZIMIDAZOLE; DERIVATIVES; ANNULATION; STRATEGIES; ACCESS;

D O I：

10.1016/j.tet.2011.06.076

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of the new benzimidazo[2,1-a]ellipticine derivatives via tandem inter and intramolecular, 5-endo,6-endo cyclization of various 9-ethyl-2-(alkynyl)carbazole-3-carbaldehydes with different 1,2-aryldiamines is reported under metal free condition in good yields. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：6934 / 6938

页数：5

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