Iodoarene-mediated one-pot preparation of 2,4,5-trisubstituted oxazoles from ketones

被引：24

作者：

Kawano, Yuhta ^{[1
]}

Togo, Hideo ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Sci, Inage Ku, Chiba 2638522, Japan

来源：

SYNLETT | 2008年 / 02期

关键词：

2,4,5-tri substituted oxazoles; one-pot reaction; MCPBA; iodoarene;

D O I：

10.1055/s-2007-100087

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Methyl-5-aryloxazole and 2-ethyl-5-aryloxazole derivatives were smoothly and efficiently obtained in one-pot manner from alkyl aryl ketones with iodoarene, m-chloroperbenzoic acid, and trifluoromethanesulfonic acid in acetonitrile and propionitrile, respectively. In these reactions, iodoarene works as a catalyst.

引用

页码：217 / 220

页数：4

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