A case of reversible posterior leukoencephalopathy syndrome caused by transient hypercoagulable state induced by infection

被引：12

作者：

Yano, Y

Kario, K

Fukunaga, T

Ohshita, T

Himeji, D

Yano, M

Nakagawa, S

Sakata, Y

Shimada, K

机构：

[1] Nango Natl Hlth Insurance Hosp, Dept Internal Med, Miyazaki 8830306, Japan

[2] Miyazaki Prefecture Miyazaki Hosp, Dept Cardiol, Miyazaki, Japan

[3] Miyazaki Prefecture Miyazaki Hosp, Dept Internal Med, Miyazaki, Japan

[4] Jichi Med Sch, Dept Cell & Mol Med, Tochigi, Japan

[5] Hiroshima Univ, Grad Sch Biomed Sci, Dept Clin Neurosci & Therapeut, Hiroshima, Japan

来源：

HYPERTENSION RESEARCH | 2005年 / 28卷 / 07期

关键词：

reversible posterior leukoencephalopathy syndrome; endothelial dysfunction; normotensive; hypercoagulable state;

D O I：

10.1291/hypres.28.619

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

We report a normotensive case of reversible posterior leukoencephalopathy syndrome caused by transient hypercoagulable state. Hypertension is the main risk factor for reversible posterior leukoencephalopathy syndrome, which is believed to occur as a result of high blood pressure-related dysfunction of cerebrovascular endothelial cells, because it commonly appears in hypertensive emergency. However, in this completely normotensive case, the typical clinical findings of reversible posterior leukoencephalopathy syndrome were triggered by transient hypercoagulable state without any blood pressure variation. The case was successfully treated with anticoagulation therapy using heparin. Thus, this case indicates that reversible posterior leukoencephalopathy syndrome is induced by cerebrovascular endothelial dysfunction, which is induced not only by high blood pressure but also hemostatic dysfunction.

引用

页码：619 / 623

页数：5

共 27 条

[1] Posterior leukoencephalopathy without severe hypertension - Utility of diffusion-weighted MRI [J].