Salivary Amylase: Digestion and Metabolic Syndrome

被引：167

作者：

des Gachons, Catherine Peyrot ^{[1
]}

Breslin, Paul A. S. ^{[1
,2
]}

机构：

[1] Monell Chem Senses Ctr, 3500 Market St, Philadelphia, PA 19104 USA

[2] Rutgers State Univ, Sch Environm & Biol Sci, Dept Nutr Sci, New Brunswick, NJ 08901 USA

来源：

CURRENT DIABETES REPORTS | 2016年 / 16卷 / 10期

关键词：

Salivary amylase; Starch digestion; AMY1 copy number variation; Glucose homeostasis; Insulin; Metabolic syndrome; COPY NUMBER VARIATION; LOW SERUM AMYLASE; ALPHA-AMYLASE; DOG DOMESTICATION; STARCH; TASTE; INSULIN; GLUCOSE; RAT; GENE;

D O I：

10.1007/s11892-016-0794-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Salivary amylase is a glucose-polymer cleavage enzyme that is produced by the salivary glands. It comprises a small portion of the total amylase excreted, which is mostly made by the pancreas. Amylases digest starch into smaller molecules, ultimately yielding maltose, which in turn is cleaved into two glucose molecules by maltase. Starch comprises a significant portion of the typical human diet for most nationalities. Given that salivary amylase is such a small portion of total amylase, it is unclear why it exists and whether it conveys an evolutionary advantage when ingesting starch. This review will consider the impact of salivary amylase on oral perception, nutrient signaling, anticipatory metabolic reflexes, blood sugar, and its clinical implications for preventing metabolic syndrome and obesity.

引用

页数：7