Ring opening reactions of N-alkyl oxazolidinones with organolithium reagents

被引：9

作者：

Jones, S ^{[1
]}

Norton, HC ^{[1
]}

机构：

[1] Univ Newcastle Upon Tyne, Sch Nat Sci Chem, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

来源：

SYNLETT | 2004年 / 02期

关键词：

acylations; amides; amino alcohols; organometallic reagents; rearrangements;

D O I：

10.1055/s-2003-44972

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of primary, secondary and aryl organolithium reagents to N-methyl and N-benzyl oxazolidin-2-ones give N-acyl amino alcohols in 30-93% yields. Application to the synthesis of an imidazoyl oxazoline is demonstrated.

引用

页码：338 / 340

页数：3

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