Redox Going with Vascular Shear Stress

被引:16
作者
Noguchi, Noriko [1 ]
Jo, Hanjoong [2 ,3 ,4 ]
机构
[1] Doshisha Univ, Fac Life & Med Sci, Dept Med Life Syst, Tatara, Kyotanabe 6100321, Japan
[2] Emory Univ, Dept Med, Div Cardiol, Atlanta, GA 30322 USA
[3] Emory Univ, Coulter Dept Biomed Engn, Georgia Inst Technol, Atlanta, GA 30322 USA
[4] Ewha Womans Univ, Dept Bioinspired Sci, Seoul, South Korea
关键词
FLOW; ATHEROSCLEROSIS; RESPONSES;
D O I
10.1089/ars.2011.4011
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Shear stress plays a critical role in the regulation of vascular biology and diseases, such as atherosclerosis, via modulation of signal transduction and redox balance. Atherosclerosis preferentially occurs in a site-specific manner linked to disturbed flow. In this Forum on Vascular Shear Stress, emerging role of redox-dependent molecular mechanisms by which shear stress regulates pro- and antiatherogenic responses in endothelial cells both in vitro and in vivo are reviewed in depth by experts. This Forum also provides comprehensive reviews regarding experimental apparatus and in vivo, ex vivo, and in vitro systems used for shear stress studies. Antioxid. Redox Signal. 15, 1367-1368.
引用
收藏
页码:1367 / 1368
页数:2
相关论文
共 15 条
[1]   Directed Stem Cell Differentiation by Fluid Mechanical Forces [J].
Adamo, Luigi ;
Garcia-Cardena, Guillermo .
ANTIOXIDANTS & REDOX SIGNALING, 2011, 15 (05) :1463-1473
[2]   Endothelial responses to mechanical stress: Where is the mechanosensor? [J].
Ali, MH ;
Schumacker, PT .
CRITICAL CARE MEDICINE, 2002, 30 (05) :S198-S206
[3]   Effects of Shear Stress and Stretch on Endothelial Function [J].
Ando, Joji ;
Yamamoto, Kimiko .
ANTIOXIDANTS & REDOX SIGNALING, 2011, 15 (05) :1389-1403
[4]   FLOW PATTERNS AND SPATIAL-DISTRIBUTION OF ATHEROSCLEROTIC LESIONS IN HUMAN CORONARY-ARTERIES [J].
ASAKURA, T ;
KARINO, T .
CIRCULATION RESEARCH, 1990, 66 (04) :1045-1066
[5]   Endoplasmic Reticulum Stress, Redox, and a Proinflammatory Environment in Athero-Susceptible Endothelium In Vivo at Sites of Complex Hemodynamic Shear Stress [J].
Davies, Peter F. ;
Civelek, Mete .
ANTIOXIDANTS & REDOX SIGNALING, 2011, 15 (05) :1427-1432
[6]   Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis [J].
Nam, Douglas ;
Ni, Chih-Wen ;
Rezvan, Amir ;
Suo, Jin ;
Budzyn, Klaudia ;
Llanos, Alexander ;
Harrison, David ;
Giddens, Don ;
Jo, Hanjoong .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2009, 297 (04) :H1535-H1543
[7]   "Go With the Flow": How Kruppel-Like Factor 2 Regulates the Vasoprotective Effects of Shear Stress [J].
Nayak, Lalitha ;
Lin, Zhiyong ;
Jain, Mukesh K. .
ANTIOXIDANTS & REDOX SIGNALING, 2011, 15 (05) :1449-1461
[8]   Flow Shear Stress and Atherosclerosis: A Matter of Site Specificity [J].
Nigro, Patrizia ;
Abe, Jun-ichi ;
Berk, Bradford C. .
ANTIOXIDANTS & REDOX SIGNALING, 2011, 15 (05) :1405-1414
[9]   Animal, In Vitro, and Ex Vivo Models of Flow-Dependent Atherosclerosis: Role of Oxidative Stress [J].
Rezvan, Amir ;
Ni, Chih-Wen ;
Alberts-Grill, Noah ;
Jo, Hanjoong .
ANTIOXIDANTS & REDOX SIGNALING, 2011, 15 (05) :1433-1448
[10]  
RUBANYI GM, 1990, BLOOD VESSELS, V27, P246