Vitiligo improvement in a patient with Ankylosing spondylitis treated with infliximab

被引：36

作者：

Simon, J. -Abraham ^{[2
]}

Burgos-Vargas, Ruben ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Hosp Gen Mexico, Fac Med, Dept Rheumatol,Serv Reumatol, Mexico City 06726, DF, Mexico

[2] CEM Hosp, Dept Internal Med, IMSS, UMAE Yucatan,Med Res Ctr, Mexico City, DF, Mexico

来源：

DERMATOLOGY | 2008年 / 216卷 / 03期

关键词：

Ankylosing spondylitis; infliximab; vitiligo; treatment; anti-TNF;

D O I：

10.1159/000112932

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Ankylosing spondylitis (AS) is a disabling disease affecting the enthesis and joints of the spine and peripheral sites. Tumour necrosis factor alpha (TNF-alpha) is a proinflammatory mediator which plays a significant role in the pathogenesis of AS. Infliximab (a chimeric monoclonal antibody which blocks the activity of TNF-alpha) is one of the most effective therapies of AS thus far. Vitiligo is a depigmenting disorder of the skin of unknown aetiology affecting 0.5-1% of the population. Here we describe the effect of infliximab on vitiligo in a patient with AS. Copyright (c) 2008 S. Karger AG, Basel.

引用

页码：234 / 235

页数：2

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