Fetal Physiology and the Transition to Extrauterine Life

被引：173

作者：

Morton, Sarah U. ^{[1
]}

Brodsky, Dara ^{[2
]}

机构：

[1] Childrens Hosp, Dept Neonatol, Harvard Neonatal Perinatal Med Training Program, Enders 9,300 Longwood Ave, Boston, MA 02216 USA

[2] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Boston, MA 02115 USA

来源：

CLINICS IN PERINATOLOGY | 2016年 / 43卷 / 03期

关键词：

Fetal physiology; Intrauterine circulation; Transition from intrauterine to extrauterine life; Transition physiology; FUNCTIONAL RESIDUAL CAPACITY; PULMONARY-CIRCULATION; DUCTUS-ARTERIOSUS; OXYGEN-SATURATION; LIQUID CLEARANCE; LUNG AERATION; ADAPTATION; TERM; MECHANISMS; EXPRESSION;

D O I：

10.1016/j.clp.2016.04.001

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The physiology of the fetus is fundamentally different from the neonate, with both structural and functional distinctions. The fetus is well-adapted to the relatively hypoxemic intrauterine environment. The transition from intrauterine to extrauterine life requires rapid, complex, and well orchestrated steps to ensure neonatal survival. This article explains the intrauterine physiology that allows the fetus to survive and then reviews the physiologic changes that occur during the transition to extrauterine life. Asphyxia fundamentally alters the physiology of transition and necessitates a thoughtful approach in the management of affected neonates.

引用

页码：395 / +

页数：14

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