Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases

被引：28
作者：
Ong, Sally S. [1 ]
Patel, Tapan P. [1 ]
Singh, Mandeep S. [1 ]
机构：
[1] Johns Hopkins Univ Hosp, Wilmer Eye Inst, Baltimore, MD 21287 USA
来源：
JOURNAL OF CLINICAL MEDICINE | 2019年 / 8卷 / 12期
关键词：
optical coherence tomography angiography; degenerative retinal diseases; retinitis pigmentosa; Stargardt disease; Best disease; choroideremia; gene therapy; retinal pigment epithelium; in vivo imaging; choriocapillaris; VASCULAR ABNORMALITIES; FUNDUS FLAVIMACULATUS; DIABETIC-RETINOPATHY; TRANSPORTER GENE; DENSITY; FEATURES; THERAPY; ABCR;
D O I：
10.3390/jcm8122078
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of retinal diseases, including inherited retinal dystrophies. In this review, we provide an overview of the evolution of OCTA technology, compare the specifications of various OCTA devices, and summarize key findings from published OCTA studies in inherited retinal dystrophies including retinitis pigmentosa, Stargardt disease, Best vitelliform macular dystrophy, and choroideremia. OCTA imaging has provided new data on characteristics of these conditions and has contributed to a deeper understanding of inherited retinal disease.
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页数：15
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