The human contactin-associated protein-like 2 gene (CNTNAP2) spans over 2 Mb of DNA at chromosome 7q35

被引：33
作者：
Nakabayashi, K
Scherer, SW
机构：
[1] Hosp Sick Children, Dept Genet, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Dept Mol & Med Genet, Toronto, ON M5G 1X8, Canada
来源：
GENOMICS | 2001年 / 73卷 / 01期
关键词：
D O I：
10.1006/geno.2001.6517
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Contactin-associated genes are members of the neurexin superfamily that encode a group of transmembrane proteins that mediate cell-cell interactions in the nervous system. To study the human contactin-associated protein-like 2 gene (CNTNAP2), we have determined its complete DNA sequence and its genomic organization to comprise 25 exons spanning greater than 2.0 Mb of DNA at 7q35, Our results indicate that CNTNAP2 encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. (C) 2001 Academic Press.
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页码：108 / 112
页数：5
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