Changes in CNTF receptor a expression in rat skeletal muscle during the recovery period after hindlimb suspension

被引:8
|
作者
Guillet, C
Huchet-Cadiou, C
Gascan, H
Léoty, C
机构
[1] CHU Angers, Lab Biol Cellulaire Neuroimmunol Neuropathol, Angers 01, France
[2] Fac Sci & Tech, CNRS, ERS 6107, Lab Physiol Gen, Nantes 03, France
来源
ACTA PHYSIOLOGICA SCANDINAVICA | 1998年 / 163卷 / 03期
关键词
ciliary neurotrophic factor; CNTF receptor alpha; hindlimb unweighting; sarcoplasmic reticulum;
D O I
10.1046/j.1365-201x.1998.00355.x
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
This study investigated whether modifications in the contractile function of rat muscle after 3 weeks of hindlimb suspension followed by different recovery periods were associated with changes in ciliary neurotrophic factor (CNTF) receptor alpha. CNTF receptor alpha was stronger in control extensor digitorum longus (EDL) than soleus. CNTF receptor alpha was increased in unweighted as compared to control soleus muscle, while no significant changes occurred in EDL muscle. Furthermore. CNTF level was not significantly modified in adult sciatic nerve.
引用
收藏
页码:273 / 278
页数:6
相关论文
共 6 条
  • [1] Changes in expression of ciliary neurotrophic factor (CNTF) and CNTF-receptor alpha after spinal cord injury
    Oyesiku, NM
    Wilcox, JN
    Wigston, DJ
    JOURNAL OF NEUROBIOLOGY, 1997, 32 (03): : 251 - 261
  • [2] Differential expression of ciliary neurotrophic factor receptor in skeletal muscle of chick and rat after nerve injury
    Ip, FCF
    Fu, AKY
    Tsim, KWK
    Ip, NY
    JOURNAL OF NEUROCHEMISTRY, 1996, 67 (04) : 1607 - 1612
  • [3] CNTF receptor alpha is expressed by magnocellular neurons and expression is upregulated in the rat supraoptic nucleus during axonal sprouting
    Watt, John A.
    Lo, David
    Cranston, Harwood J.
    Paden, Charles M.
    EXPERIMENTAL NEUROLOGY, 2009, 215 (01) : 135 - 141
  • [4] Early changes of type 2B fibers after denervation of rat EDL skeletal muscle
    Germinario, E
    Esposito, A
    Megighian, A
    Midrio, M
    Biral, D
    Betto, R
    Danieli-Betto, D
    JOURNAL OF APPLIED PHYSIOLOGY, 2002, 92 (05) : 2045 - 2052
  • [5] Predominant cause of prolonged low-frequency force depression changes during recovery after in situ fatiguing stimulation of rat fast-twitch muscle
    Watanabe, Daiki
    Wada, Masanobu
    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2016, 311 (05) : R919 - R929
  • [6] Contribution of impaired myofibril and ryanodine receptor function to prolonged low-frequency force depression after in situ stimulation in rat skeletal muscle
    Watanabe, Daiki
    Kanzaki, Keita
    Kuratani, Mai
    Matsunaga, Satoshi
    Yanaka, Noriyuki
    Wada, Masanobu
    JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 2015, 36 (03) : 275 - 286