Recent developments in potentiometric biosensors for biomedical analysis

被引：98
作者：
Koncki, Robert [1 ]
机构：
[1] Univ Warsaw, Dept Chem, PL-02093 Warsaw, Poland
来源：
ANALYTICA CHIMICA ACTA | 2007年 / 599卷 / 01期
关键词：
clinical analysis; potentiometry; biosensors; biocatalysis; bioaffinity;
D O I：
10.1016/j.aca.2007.08.003
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A large variety of potentiometric biosensors is developed using biocatalytic and bioaffinity-based biosensing schemes. However, only few of them could be applied for the biomedical analysis. The most promising are those for the detection of main products of protein metabolism, namely urea and creatinine. A novel group of potentiometric biosensors is constituted by bioaffinity-based devices that could be used for immunoassays or genoanalysis. This paper reviews the recent trends in these fields as well as discusses advantages, limitations and pitfalls of the developed biosensors. Some potentiometric biosensors useful for real biomedical analysis are reported in detail. (c) 2007 Elsevier B.V. All rights reserved.
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收藏
页码：7 / 15
页数：9
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