Practical Three-Minute Synthesis of Acid-Coated Fluorescent Carbon Dots with Tuneable Core Structure

被引：44

作者：

Hill, Stephen A. ^{[1
]}

Benito-Alifonso, David ^{[1
]}

Davis, Sean A. ^{[1
]}

Morgan, David J. ^{[2
]}

Berry, Monica ^{[3
]}

Galan, M. Carmen ^{[1
]}

机构：

[1] Univ Bristol, Sch Chem, Cantocks Close, Bristol BS8 1TS, Avon, England

[2] Cardiff Univ, Sch Chem, Cardiff Catalysis Inst, Pk Pl, Cardiff CF10 3AT, S Glam, Wales

[3] Univ Bristol, Sch Phys, Bristol BS8 1TL, Avon, England

来源：

SCIENTIFIC REPORTS | 2018年 / 8卷

基金：

英国工程与自然科学研究理事会;

关键词：

GRAPHENE QUANTUM DOTS; SENSITIVE DETECTION; NANODOTS SYNTHESIS; ELECTRON-TRANSFER; GENE DELIVERY; FE3+; NITROGEN; GLUCOSE; GENERATION; PYRAZINES;

D O I：

10.1038/s41598-018-29674-2

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We report a one-pot, three-minute synthesis of carboxylic acid-decorated fluorescent carbon dots (COOH-FCDs) with tuneable core morphology dependent on the surface passivating agent. Mechanism investigations highlighted the presence of key pyrazine and polyhydroxyl aromatic motifs, which are formed from the degradation of glucosamine in the presence of a bifunctional linker bearing acid and amine groups. The novel COOH-FCDs are selective Fe3+ and hemin sensors. Furthermore, the FCDs are shown to be non-toxic, fluorescent bioimaging agents for cancer cells.

引用

页数：10

共 67 条

[1] Atomic spectrometric methods for the determination of metals and metalloids in automotive fuels - A review [J].

Andrade Korn, Maria das Gracas ;

Sodre dos Santos, Denilson Santana ;

Welz, Bernhard ;

Rodrigues Vale, Maria Goreti ;

Teixeira, Alete Paixao ;

Lima, Daniel de Castro ;

Ferreira, Sergio Luis Costa .

TALANTA, 2007, 73 (01) :1-11

[2] Luminescent Carbon Nanodots: Emergent Nanolights [J].

Baker, Sheila N. ;

Baker, Gary A. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (38) :6726-6744

[3] Lactose as a "Trojan Horse" for Quantum Dot Cell Transport [J].

Benito-Alifonso, David ;

Tremel, Shirley ;

Hou, Bo ;

Lockyear, Harriet ;

Mantell, Judith ;

Fermin, David J. ;

Verkade, Paul ;

Berry, Monica ;

Galan, M. Carmen .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (03) :810-814

[4] Fructosazine, a Polyhydroxyalkylpyrazine with Antimicrobial Activity: Mechanism of Inhibition against Extremely Heat Resistant Escherichia coli [J].

Bhattacherjee, Abhishek ;

Hrynets, Yuliya ;

Betti, Mirko .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2016, 64 (45) :8530-8539

[5] Selective Sensing of Fe3+ and Al3+ Ions and Detection of 2,4,6-Trinitrophenol by a Water-Stable Terbium-Based Metal-Organic Framework [J].

Cao, Li-Hui ;

Shi, Fang ;

Zhang, Wen-Min ;

Zang, Shuang-Quan ;

Mak, Thomas C. W. .

CHEMISTRY-A EUROPEAN JOURNAL, 2015, 21 (44) :15705-15712

[6] Fluorescent Sensors for Measuring Metal Ions in Living Systems [J].

Carter, Kyle P. ;

Young, Alexandra M. ;

Palmer, Amy E. .

CHEMICAL REVIEWS, 2014, 114 (08) :4564-4601

[7] Polycation-b-Polyzwitterion Copolymer Grafted Luminescent Carbon Dots As a Multifunctional Platform for Serum-Resistant Gene Delivery and Bioimaging [J].

Cheng, Lu ;

Li, Yongmao ;

Zhai, Xinyun ;

Xu, Bing ;

Cao, Zhiqiang ;

Liu, Wenguang .

ACS APPLIED MATERIALS & INTERFACES, 2014, 6 (22) :20487-20497

[8] Nitrogen and sulfur co-doped carbon dots with strong blue luminescence [J].

Ding, Hui ;

Wei, Ji-Shi ;

Xiong, Huan-Ming .

NANOSCALE, 2014, 6 (22) :13817-13823

[9] Sensing applications of luminescent carbon based dots [J].

Dong, Yongqiang ;

Cai, Jianhua ;

You, Xu ;

Chi, Yuwu .

ANALYST, 2015, 140 (22) :7468-7486

[10] Carbon-Based Dots Co-doped with Nitrogen and Sulfur for High Quantum Yield and Excitation-Independent Emission [J].

Dong, Yongqiang ;

Pang, Hongchang ;

Yang, Hong Bin ;

Guo, Chunxian ;

Shao, Jingwei ;

Chi, Yuwu ;

Li, Chang Ming ;

Yu, Ting .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (30) :7800-7804

← 1 2 3 4 5 6 7 →