Body weight status and obstructive sleep apnea in children

被引:80
作者
Kang, K-T [1 ,2 ]
Lee, P-L [3 ,4 ]
Weng, W-C [5 ]
Hsu, W-C [1 ,3 ]
机构
[1] Natl Taiwan Univ Hosp, Dept Otolaryngol, Taipei, Taiwan
[2] Taipei Hosp, Dept Otolaryngol, Dept Hlth, New Taipei City, Taiwan
[3] Natl Taiwan Univ Hosp, Sleep Ctr, Taipei, Taiwan
[4] Natl Taiwan Univ Hosp, Dept Internal Med, Taipei 100, Taiwan
[5] Natl Taiwan Univ Hosp, Dept Pediat, Taipei 10016, Taiwan
关键词
weight status; obese; underweight; obstructive sleep apnea; polysomnography; children; UPPER AIRWAY-OBSTRUCTION; HYPOPNEA SYNDROME; POLYSOMNOGRAPHY; DIAGNOSIS; OBESITY; GENDER;
D O I
10.1038/ijo.2012.5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE: The relationship between weight status, adenotonsillar hypertrophy and obstructive sleep apnea (OSA) in children has not yet been well studied. As the sleep parameters may show a disparity in different weight statuses, this study examined the relationship between the data of over-night polysomnography and different weight statuses, as well as the impact of adenotonsillar hypertrophy on children with OSA. METHODS: Children with sleep disturbances were recruited from our clinics. Standard physical examinations, history taking, lateral neck roentgenography, and full-night polysomnography were obtained. Children were divided into four groups based on the age-and gender-corrected body mass index (BMI): underweight, normal weight, overweight and obese. An adenoidal/nasopharyngeal ratio of more than 0.67 was considered adenoidal hypertrophy. Tonsillar hypertrophy was defined as having Grade III tonsils or above. RESULTS: From July 2006 to January 2009, 197 children were included in this study. Obese children had a significantly higher apnea-hypopnea index (AHI), obstructive apnea index and lower minimum oxygen saturation (MinSaO(2)) than those of the other groups. Underweight children had the second highest AHI. A negative correlation was also found between BMI z scores and MinSaO(2) (r = 0.194; P = 0.007). Children with tonsillar hypertrophy (P = 0.001) were associated with a higher risk of having OSA. The risk of having OSA was significantly higher in obese children (P = 0.001) and underweight children (P = 0.043) than in those with a normal weight. CONCLUSION: Obesity, underweight status and tonsillar hypertrophy are associated with children having OSA, and obese children have a significantly higher risk than children with underweight status.
引用
收藏
页码:920 / 924
页数:5
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