A simultaneous PET/MRI scanner based on RatCAP in small animals

被引：19

作者：

Schyler, D. ^{[1
]}

Vaska, P.

Tomasi, D.

Woody, C.

Maramraju, S-H ^{[2
]}

Southekal, S. ^{[2
]}

Pratte, J-F

Junnarkar, S.

Solis-Najera, S.

Krishnamoorthy, S. ^{[2
]}

Kriplani, A. ^{[2
]}

Stoll, S.

机构：

[1] Brookhaven Natl Lab, Upton, NY 11973 USA

[2] SUNY Stony Brook, Biomed Engn dept, Stony Brook, NY USA

来源：

2007 IEEE NUCLEAR SCIENCE SYMPOSIUM CONFERENCE RECORD, VOLS 1-11 | 2007年

关键词：

D O I：

10.1109/NSSMIC.2007.4436833

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

The ability to acquire high resolution anatomical data as well as quantitative functional information in vivo is becoming an increasingly important factor in the diagnosis of disease. Simultaneous acquisition of PET and MRI data would provide essentially perfect co-registration between the two images which is particularly important for tissues whose position and shape can change between sequential scans. RatCAP is a complete 3D tomograph that is designed to image the brain of an awake rat. A special MRI coil composed of 2 saddle elements working in quadrature mode was mounted on a Delrin cylinder specifically designed to fit inside the RatCAP but allowing the rat's head to be placed inside as well. Simultaneous PET/MRI images of the rat brain have been acquired in a 4T MRI scanner using the RatCAP detector, with minimal effect on MRI images.

引用

页码：3256 / +

页数：2

共 16 条

[1]

Beyer T, 2004, J NUCL MED, V45, p25S

[2] Positron emission tomography/computed tomography-imaging protocols, artifacts, and pitfalls [J].

Bockisch, A ;

Beyer, T ;

Antoch, G ;

Freudenberg, LS ;

Kühl, H ;

Debatin, JF ;

Müller, SP .

MOLECULAR IMAGING AND BIOLOGY, 2004, 6 (04) :188-199

[3]

JUNNARKAR SS, 2005, IEEE T NUCL SCI, V2

[4] PET-CT in clinical oncology [J].

Maldonado, A. ;

Gonzalez-Alenda, F. J. ;

Alonso, M. ;

Sierra, J. M. .

CLINICAL & TRANSLATIONAL ONCOLOGY, 2007, 9 (08) :494-505

[5] Simultaneous PET and NMR [J].

Marsden, PK ;

Strul, D ;

Keevil, SF ;

Williams, SCR ;

Cash, D .

BRITISH JOURNAL OF RADIOLOGY, 2002, 75 :S53-S59

[6]

PICHLER B, 1997, NUCL SCI S 1997 IEEE, V2, P1237

[7]

Pichler BJ, 2006, J NUCL MED, V47, P639

[8] Front-end electronics for the RatCAP mobile animal PET scanner [J].

Pratte, JF ;

De Geronimo, G ;

Junnarkar, S ;

O'Connor, P ;

Yu, B ;

Robert, S ;

Radeka, V ;

Woody, C ;

Stoll, S ;

Vaska, P ;

Kandasamy, A ;

Lecomte, R ;

Fontaine, R .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2004, 51 (04) :1318-1323

[9]

PRATTE JF, 2004, IEEE T NUCL SCI, V51

[10] A novel APD-based detector module for multi-modality PET/SPECT/CT scanners [J].

Saoudi, A ;

Lecomte, R .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1999, 46 (03) :479-484

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