Liver transplantation in patients with a history of migration-A German single center comparative analysis

被引:3
作者
Bucher, Julian Nikolaus [1 ]
Koenig, Maximilian [1 ]
Schoenberg, Markus Bo [1 ]
Crispin, Alexander [2 ]
Thomas, Michael [1 ]
Angele, Martin Kurt [1 ]
Eser-Valeri, Daniela [3 ]
Gerbes, Alexander Lutz [4 ,5 ,6 ]
Werner, Jens [1 ]
Guba, Markus Otto [1 ,5 ,6 ]
机构
[1] Ludwig Maximilians Univ Munchen, Dept Gen Visceral & Transplant Surg, Munich, Germany
[2] Ludwig Maximilians Univ Munchen, Inst Med Informat Biometry & Epidemiol, Munich, Germany
[3] Ludwig Maximilians Univ Munchen, Dept Psychiat, Munich, Germany
[4] Ludwig Maximilians Univ Munchen, Dept Med 2, Munich, Germany
[5] Ludwig Maximilians Univ Munchen, Transplantat Ctr Munich, Munich, Germany
[6] Ludwig Maximilians Univ Munchen, Liver Ctr Munich, Munich, Germany
关键词
GRAFT-SURVIVAL; RENAL-TRANSPLANTATION; RACE; NETHERLANDS; ASSOCIATION; POPULATION; MIGRANTS; OUTCOMES; ACCESS;
D O I
10.1371/journal.pone.0224116
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Liver transplant (LT) programs in Germany increasingly face a multiethnic patient population. To date no outcome data for LT in patients with a history of migration is available for Germany. This complicates decision-making before wait-listing such patients. We conducted a single-center cohort analysis of all primary LT between April 2007 and December 2015, stratified for the history of migration to investigate differences in the outcome. We found transplant rates resembling the proportion of persons with a history of migration in the general public in the region of our center. Differences were found concerning age at LT and prevalence of underlying diseases. Re-Transplant rates, Kaplan-Meier Estimates for overall survival, also after stratification for viral hepatitis, sex, ethnicity or presence of a language barrier showed no statistical differences. The multivariate analysis showed no migration related covariate associated with a negative outcome. These results stand in contrast to most of the previous evidence from North America and the UK and need to be taken into consideration during the wait-listing process of patients with a history of migration in need of a LT in centers in the Eurotransplant region.
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相关论文
共 33 条
[1]  
Anna Lutz FH, BAYERISCHES STAATSMI, P34
[2]  
[Anonymous], 2009, INTERAGENCY LANGUAGE
[3]  
[Anonymous], 2001, UNABHANGIGE KOMMISSI
[4]   The MELD score in patients awaiting liver transplant: Strengths and weaknesses [J].
Bernardi, Mauro ;
Gitto, Stefano ;
Biselli, Maurizio .
JOURNAL OF HEPATOLOGY, 2011, 54 (06) :1297-1306
[5]  
Bradby H, WHO HLTH EVIDENCE NE
[6]   ETHNIC VARIATIONS IN PATIENT AND GRAFT-SURVIVAL AFTER LIVER-TRANSPLANTATION - IDENTIFICATION OF A NEW RISK FACTOR FOR CHRONIC ALLOGRAFT-REJECTION [J].
DEVLIN, JJ ;
OGRADY, JG ;
TAN, KC ;
CALNE, RY ;
WILLIAMS, R .
TRANSPLANTATION, 1993, 56 (06) :1381-1384
[7]   Renal transplantation in indo-asian patients in the UK [J].
Dooldeniya, MD ;
Dupont, PJ ;
He, X ;
Johnson, RJ ;
Joshi, T ;
Basra, R ;
Johnston, A ;
Warrens, AN .
AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (04) :761-769
[8]  
Dossetor J B, 1995, Curr Opin Nephrol Hypertens, V4, P498, DOI 10.1097/00041552-199511000-00007
[9]   Insurance Type and Solid Organ Transplantation Outcomes: A Historical Perspective on How Medicaid Expansion Might Impact Transplantation Outcomes [J].
DuBay, Derek A. ;
MacLennan, Paul A. ;
Reed, Rhiannon D. ;
Shelton, Brittany A. ;
Redden, David T. ;
Fouad, Mona ;
Martin, Michelle Y. ;
Gray, Stephen H. ;
White, Jared A. ;
Eckhoff, Devin E. ;
Locke, Jayme E. .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2016, 223 (04) :611-+
[10]  
European Centre for Disease Prevention and Control, 2014, ASS BURD KEY INF DIS, P40