Effects of Hoelen on the efferent activity of the gastric vagus nerve in the rat

被引：21

作者：

Okui, Y ^{[1
]}

Morita, M ^{[1
]}

Iizuka, A ^{[1
]}

Komatsu, Y ^{[1
]}

Okada, M ^{[1
]}

Maruno, M ^{[1
]}

Niijima, A ^{[1
]}

机构：

[1] NIIGATA UNIV, SCH MED, DEPT PHYSIOL, NIIGATA 951, JAPAN

来源：

JAPANESE JOURNAL OF PHARMACOLOGY | 1996年 / 72卷 / 01期

关键词：

vagus nerve; gastric branch; Hoelen;

D O I：

10.1254/jjp.72.71

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Hoelen is used to treat gastric disease in Eastern traditional medicine. The efferent activity on the gastric vagus nerve was studied in the rat, and the activity was found to increase after administration of Hoelen into the duodenum. In addition, we examined the effect of Hoelen fractions. Both the fraction containing polysaccharide and the triterpenoid-rich fraction increased activity significantly. Hoelen would thus appear useful for treating gastric disease by activating efferent activity of the gastric vagus nerve through the action of triterpenoid and polysaccharide.

引用

页码：71 / 73

页数：3

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