Efficient synthesis of 2,3-dimethoxy-5-methyl-6-morpholinomethyl-1,4-benzoquinone hydrochloride

被引：3

作者：

Wang, Jin ^{[1
]}

Liao, Teng-huo-sheng ^{[2
]}

Yang, Jian ^{[1
]}

机构：

[1] Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kunming 650224, Yunnan, Peoples R China

[2] Zhejiang MENOVO Pharmaceut Co Ltd, ShangYu 312300, Zhejiang, Peoples R China

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2015年 / 70卷 / 04期

关键词：

benzoquinone derivative; blanc reaction; coenzyme Q analogs; COENZYME-Q ANALOGS; UBIQUINONE; IDEBENONE; CHAIN;

D O I：

10.1515/znb-2014-0208

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The title compound (5) was prepared by a reaction sequence starting from 2,3,4,5-tetramethoxytoluene (1) via the Blanc reaction, oxidation and alkylation. The described method provides a good yield of the C-6 heterocyclic-substituted benzoquinone derivative and is suitable for the synthesis of other benzoquinone derivatives.

引用

页码：221 / 223

页数：3

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