New multicomponent approach for the synthesis of benzo[c]coumarin derivatives over MgO under solvent-free conditions

被引:22
作者
Valizadeh, Hassan [1 ]
Fakhari, Ashraf [1 ]
机构
[1] Azarbaijan Univ Tarbiat Moallem, Dept Chem, Fac Sci, Tabriz, Iran
关键词
Benzocoumarin; Solvent-free; Multicomponent reaction; MgO; ONE-POT SYNTHESIS; IONIC LIQUID; EFFICIENT; ABSENCE; CATALYST;
D O I
10.1007/s11030-010-9260-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this study, a three-component one-pot synthesis of select 5-amino-6-cyano-3-hydroxybenzo[c]coumarin compounds derived from salicylaldehydes, malononitrile, and ethyl acetoacetate is reported. The reaction is conducted on grinding over MgO at room temperature resulting in good yields.
引用
收藏
页码:233 / 237
页数:5
相关论文
共 35 条
[1]  
Anastas P., 1998, GREEN CHEM THEORY PR
[2]   A heterogeneous strong basic Mg/La mixed oxide catalyst for efficient synthesis of polyfunctionalized pyrans [J].
Babu, N. Seshu ;
Pasha, Nayeem ;
Rao, K. T. Venkateswara ;
Prasad, P. S. Sai ;
Lingalah, N. .
TETRAHEDRON LETTERS, 2008, 49 (17) :2730-2733
[3]  
Bagley MC, 2006, TOP HETEROCYCLIC CHE, V1, P31
[4]  
Bienaymé H, 2000, CHEM-EUR J, V6, P3321, DOI 10.1002/1521-3765(20000915)6:18<3321::AID-CHEM3321>3.0.CO
[5]  
2-A
[6]   A novel microwave-mediated one-pot synthesis of indolizines via a three-component reaction [J].
Bora, U ;
Saikia, A ;
Boruah, RC .
ORGANIC LETTERS, 2003, 5 (04) :435-438
[7]   High-throughput synthesis of N3-acylated dihydropyrimidines combining microwave-assisted synthesis and scavenging techniques [J].
Dallinger, D ;
Gorobets, NY ;
Kappe, CO .
ORGANIC LETTERS, 2003, 5 (08) :1205-1208
[8]   A novel catalyst for the Knoevenagel condensation of aldehydes with malononitrile and ethyl cyanoacetate under solvent free conditions [J].
Gawande, Manoj B. ;
Jayaram, Radha V. .
CATALYSIS COMMUNICATIONS, 2006, 7 (12) :931-935
[9]   Efficient library synthesis of imidazoles using a multicomponent reaction and microwave irradiation [J].
Gelens, E ;
De Kanter, FJJ ;
Schmitz, RF ;
Sliedregt, LAJM ;
Van Steen, BJ ;
Kruse, CG ;
Leurs, R ;
Groen', MB ;
Orru, RA .
MOLECULAR DIVERSITY, 2006, 10 (01) :17-22
[10]  
HAMMAD A, 1990, J CHEM SOC PAKISTAN, V12, P292