Synthesis, Physicochemical, and Biological Studies of Complexes of 2-Aminobenzohydrazine with Co(II), Ni(II), Cu(II), and Zn(II) Chlorides

Coordination complexes of modified hydrazine bearing unit were synthesized with transition metals viz. Cu(II), Co(II), Ni(II), and Zn(II). The ligand amino benzohydrazide (ABH) was synthesized by replacing the methoxy moiety of methyl anthranilate with the nitrogen of the hydrazine hydrate, creating new coordination site. The coordination complexes were made by the reaction of ABH ligand with dehydrated metal chloride in inert environment. The compositions and structures of ligand and coordination complexes were elucidated employing physical measurements such as microanalysis, NMR, IR, UV-visible spectroscopy, magnetic, and conductance measurements. The results revealed the composition as M(ABH)Cl2. All of them exhibited tetrahedral geometry. Thermal studies of these metal complexes reveal the Irving William series trend regarding their stabilities. Antibacterial and antifungal inhibitions were also tested in order to determine the effectiveness of these complexes.