Value of Dual-Energy Computed Tomography for Diagnosing Cervical Lymph Node Metastasis in Patients With Papillary Thyroid Cancer

被引：30

作者：

He, Muzhen ^{[1
]}

Lin, Cailing ^{[2
]}

Yin, Lei ^{[1
]}

Lin, Yang ^{[3
]}

Zhang, Shengjian ^{[4
,5
]}

Ma, Mingping ^{[1
]}

机构：

[1] Fujian Med Univ, Fujian Prov Hosp, Prov Clin Coll, Dept Radiol, Fuzhou, Fujian, Peoples R China

[2] Fujian Med Univ, Fujian Prov Hosp, Prov Clin Coll, Dept Surg Oncol, Fuzhou, Fujian, Peoples R China

[3] Siemens Healthcare Ltd, Shanghai, Peoples R China

[4] Fudan Univ, Canc Hosp Inst, Dept Radiol, Shanghai, Peoples R China

[5] Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai, Peoples R China

来源：

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | 2019年 / 43卷 / 06期

关键词：

papillary thyroid carcinoma; lymph node; tomography; x-ray computed; spectral imaging; PREOPERATIVE DIAGNOSIS; CT; CARCINOMA; ULTRASONOGRAPHY; MANAGEMENT; ULTRASOUND; PERFORMANCE;

D O I：

10.1097/RCT.0000000000000927

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Objective The objective of this study was to determine the value of dual-energy computed tomography (DECT) for the diagnosis of cervical lymph node metastasis in papillary thyroid cancer. Methods The normalized iodine concentration (NIC) and the slope of the spectral Hounsfield unit curve (lambda(HU)) in the arterial and venous phases were measured using iodine-overlay images and spectral curves. Quantitative DECT data and qualitative conventional CT data were analyzed by radiologists. Results The best qualitative parameter for lymph node metastasis detection was obvious node enhancement, and the best quantitative parameter for detection was arterial-phase NIC, which showed high sensitivity, specificity, and accuracy values at an optimal threshold of 25.8%. The best combination of qualitative and quantitative parameters consisted of obvious enhancement and arterial-phase NIC; this combination showed a sensitivity of 90.8% and a specificity of 80.5%. Conclusions The DECT quantitative parameters NIC and lambda(HU) can be an additional tool to diagnose cervical lymph node metastasis.

引用

页码：970 / 975

页数：6

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