IGF-I: Panacea or Poison?

被引：3

作者：

LeRoith, Derek ^{[1
]}

机构：

[1] Dept Med, Div Endocrinol Diabet & Bone Dis, Metab Inst, New York, NY 10029 USA

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 2010年 / 95卷 / 10期

关键词：

GROWTH-FACTOR-I; COLORECTAL-CANCER RISK; CARDIAC-HYPERTROPHY; FACTOR (IGF)-I; BINDING PROTEIN-3; TRANSGENIC MICE; INSULIN; OVEREXPRESSION; PROGRESSION; DISEASE;

D O I：

10.1210/jc.2010-1737

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：4549 / 4551

页数：3

共 20 条

[1] Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic aftrations in the circulating insulin-like growth factor axis but does not reduce tumor progression [J].

Anzo, Makoto ;

Cobb, Laura J. ;

Hwang, David L. ;

Mehta, Hemal ;

Said, Jonathan W. ;

Yakar, Shoshana ;

LeRoith, Derek ;

Cohen, Pinchas .

CANCER RESEARCH, 2008, 68 (09) :3342-3349

[2] Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease [J].

Belfiore, Antonino ;

Frasca, Francesco ;

Pandini, Giusepe ;

Sciacca, Laura ;

Vigneri, Riccardo .

ENDOCRINE REVIEWS, 2009, 30 (06) :586-623

[3] Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice [J].

Delaughter, MC ;

Taffet, GE ;

Fiorotto, ML ;

Entman, ML ;

Schwartz, RJ .

FASEB JOURNAL, 1999, 13 (14) :1923-1929

[4] The role of insulin-like signalling in the regulation of ageing [J].

Holzenberger, M .

HORMONE RESEARCH, 2004, 62 :89-92

[5] Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research [J].

Hursting, Stephen D. ;

Smith, Sarah M. ;

Lashinger, Laura M. ;

Harvey, Alison E. ;

Perkins, Susan N. .

CARCINOGENESIS, 2010, 31 (01) :83-89

[6] Cancers associated with acromegaly [J].

Jenkins, Paul J. .

NEUROENDOCRINOLOGY, 2006, 83 (3-4) :218-223

[7] Insulin-like growth factor (IGF) I, -II, and IGF binding protein-3 and risk of ischemic stroke [J].

Johnsen, SP ;

Hundborg, HH ;

Sorensen, HT ;

Orskov, H ;

Tjonneland, A ;

Overvad, K ;

Jorgensen, JOL .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 90 (11) :5937-5941

[8] Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease - A population-based case-control study [J].

Juul, A ;

Scheike, T ;

Davidsen, M ;

Gyllenborg, J ;

Jorgensen, T .

CIRCULATION, 2002, 106 (08) :939-944

[9] Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women [J].

Kaaks, R ;

Toniolo, P ;

Akhmedkhanov, A ;

Lukanova, A ;

Biessy, C ;

Dechaud, H ;

Rinaldi, S ;

Zeleniuch-Jacquotte, A ;

Shore, RE ;

Riboli, E .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (19) :1592-1600

[10] Insulin-Like Growth Factor I Receptor Signaling Is Required for Exercise-Induced Cardiac Hypertrophy [J].

Kim, Jaetaek ;

Wende, Adam R. ;

Sena, Sandra ;

Theobald, Heather A. ;

Soto, Jamie ;

Sloan, Crystal ;

Wayment, Benjamin E. ;

Litwin, Sheldon E. ;

Holzenberger, Martin ;

LeRoith, Derek ;

Abel, E. Dale .

MOLECULAR ENDOCRINOLOGY, 2008, 22 (11) :2531-2543

← 1 2 →