Optimization in computational systems biology

被引：167
作者：
Banga, Julio R. [1 ]
机构：
[1] CSIC Spanish Council Sci Res, Inst Invest Marinas, Vigo 36208, Spain
来源：
BMC SYSTEMS BIOLOGY | 2008年 / 2卷
关键词：
D O I：
10.1186/1752-0509-2-47
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Optimization aims to make a system or design as effective or functional as possible. Mathematical optimization methods are widely used in engineering, economics and science. This commentary is focused on applications of mathematical optimization in computational systems biology. Examples are given where optimization methods are used for topics ranging from model building and optimal experimental design to metabolic engineering and synthetic biology. Finally, several perspectives for future research are outlined.
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页数：7
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