Emerging Concepts and Novel Strategies in Radiation Therapy for Laryngeal Cancer Management

被引：32

作者：

Gamez, Mauricio E. ^{[1
]}

Blakaj, Adriana ^{[2
]}

Zoller, Wesley ^{[1
]}

Bonomi, Marcelo ^{[3
]}

Blakaj, Dukagjin M. ^{[1
]}

机构：

[1] Ohio State Univ, Wexner Med Ctr, Div Radiat Oncol, Columbus, OH 43210 USA

[2] Yale Sch Med, Dept Therapeut Radiol, 35 Pk St, New Haven, CT 06519 USA

[3] Ohio State Univ, Wexner Med Ctr, Dept Internal Med, Div Med Oncol, 320 West 10th Ave, Columbus, OH 43210 USA

来源：

CANCERS | 2020年 / 12卷 / 06期

关键词：

laryngeal cancer; radiotherapy; IMRT; IGRT; SABR; de-escalation therapy; SQUAMOUS-CELL CARCINOMA; VOCAL CORD IRRADIATION; NECK-CANCER; GLOTTIC CARCINOMA; RANDOMIZED-TRIAL; TUMOR VOLUME; CONCURRENT CHEMORADIOTHERAPY; VOICE QUALITY; LASER-SURGERY; FRACTION SIZE;

D O I：

10.3390/cancers12061651

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Laryngeal squamous cell carcinoma is the second most common head and neck cancer. Its pathogenesis is strongly associated with smoking. The management of this disease is challenging and mandates multidisciplinary care. Currently, accepted treatment modalities include surgery, radiation therapy, and chemotherapy-all focused on improving survival while preserving organ function. Despite changes in smoking patterns resulting in a declining incidence of laryngeal cancer, the overall outcomes for this disease have not improved in the recent past, likely due to changes in treatment patterns and treatment-related toxicities. Here, we review emerging concepts and novel strategies in the use of radiation therapy in the management of laryngeal squamous cell carcinoma that could improve the relationship between tumor control and normal tissue damage (therapeutic ratio).

引用

页码：1 / 21

页数：21

共 99 条

[1] Voice Quality After Treatment of Early Vocal Cord Cancer: A Randomized Trial Comparing Laser Surgery With Radiation Therapy [J].

Aaltonen, Leena-Maija ;

Rautiainen, Noora ;

Sellman, Jaana ;

Saarilahti, Kauko ;

Makitie, Antti ;

Rihkanen, Heikki ;

Laranne, Jussi ;

Kleemola, Leenamaija ;

Wigren, Tuija ;

Sala, Eeva ;

Lindholm, Paula ;

Grenman, Reidar ;

Joensuu, Heikki .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2014, 90 (02) :255-260

[2] Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach [J].

Aerts, Hugo J. W. L. ;

Velazquez, Emmanuel Rios ;

Leijenaar, Ralph T. H. ;

Parmar, Chintan ;

Grossmann, Patrick ;

Cavalho, Sara ;

Bussink, Johan ;

Monshouwer, Rene ;

Haibe-Kains, Benjamin ;

Rietveld, Derek ;

Hoebers, Frank ;

Rietbergen, Michelle M. ;

Leemans, C. Rene ;

Dekker, Andre ;

Quackenbush, John ;

Gillies, Robert J. ;

Lambin, Philippe .

NATURE COMMUNICATIONS, 2014, 5

[3] Radiation therapy for T2N0 laryngeal cancer: A retrospective analysis for the impact of concurrent chemotherapy on local control [J].

Akimoto, T ;

Nonaka, T ;

Kitamoto, Y ;

Ishikawa, H ;

Ninomiya, H ;

Chikamatsu, K ;

Furuya, N ;

Hayakawa, K ;

Mitsuhashi, N ;

Nakano, T .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 64 (04) :995-1001

[4] Single Vocal Cord Irradiation: Image Guided Intensity Modulated Hypofractionated Radiation Therapy for T1a Glottic Cancer: Early Clinical Results [J].

Al-Mamgani, Abrahim ;

Kwa, Stefan L. S. ;

Tans, Lisa ;

Moring, Michael ;

Fransen, Dennie ;

Mehilal, Robert ;

Verduijn, Gerda M. ;

de Jong, Rob J. Baatenburg ;

Heijmen, Ben J. M. ;

Levendag, Peter C. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2015, 93 (02) :337-343

[5] Individual Field Simultaneous Optimization (IFSO) in spot scanning proton therapy of head and neck cancers [J].

Anand, Aman ;

Bues, Martin ;

Gamez, Mauricio E. ;

Stefan, Corbin ;

Patel, Samir H. .

MEDICAL DOSIMETRY, 2019, 44 (04) :375-378

[6]

[Anonymous], CLIN CANC RES

[7]

[Anonymous], ANN MAL OREILLE LARY

[8] Phase II randomized trial of radiation therapy, cetuximab, and pemetrexed with or without bevacizumab in patients with locally advanced head and neck canceraEuro [J].

Argiris, A. ;

Bauman, J. E. ;

Ohr, J. ;

Gooding, W. E. ;

Heron, D. E. ;

Duvvuri, U. ;

Kubicek, G. J. ;

Posluszny, D. M. ;

Vassilakopoulou, M. ;

Kim, S. ;

Grandis, J. R. ;

Johnson, J. T. ;

Gibson, M. K. ;

Clump, D. A. ;

Flaherty, J. T. ;

Chiosea, S. I. ;

Branstetter, B. ;

Ferris, R. L. .

ANNALS OF ONCOLOGY, 2016, 27 (08) :1594-1600

[9] WEEKLY VOLUME AND DOSIMETRIC CHANGES DURING CHEMORADIOTHERAPY WITH INTENSITY-MODULATED RADIATION THERAPY FOR HEAD AND NECK CANCER: A PROSPECTIVE OBSERVATIONAL STUDY [J].

Bhide, Shreerang A. ;

Davies, Mark ;

Burke, Kevin ;

McNair, Helen A. ;

Hansen, Vibeke ;

Barbachano, Y. ;

El-Hariry, I. A. ;

Newbold, Kate ;

Harrington, Kevin J. ;

Nutting, Christopher M. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 76 (05) :1360-1368

[10] Importance of Radiation Oncologist Experience Among Patients With Head-and-Neck Cancer Treated With Intensity-Modulated Radiation Therapy [J].

Boero, Isabel J. ;

Paravati, Anthony J. ;

Xu, Beibei ;

Cohen, Ezra E. W. ;

Mell, Loren K. ;

Quynh-Thu Le ;

Murphy, James D. .

JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (07) :684-+

← 1 2 3 4 5 6 7 8 9 10 →