Pleuroparenchymal fibroelastosis in patients with pulmonary disease secondary to bone marrow transplantation

被引：126

作者：

von der Thuesen, Jan H. ^{[1
]}

Hansell, David M. ^{[2
]}

Tominaga, Masaki ^{[1
,3
]}

Veys, Paul A. ^{[4
]}

Ashworth, Michael T. ^{[5
]}

Owens, Catherine M. ^{[6
]}

Nicholson, Andrew G. ^{[1
]}

机构：

[1] Royal Brompton & Harefield NHS Fdn Trust, Dept Histopathol, London SW3 6NP, England

[2] Royal Brompton & Harefield NHS Fdn Trust, Dept Radiol, London SW3 6NP, England

[3] Toyama Univ Hosp, Dept Pathol, Toyama, Japan

[4] Great Ormond St Hosp Sick Children, Dept Bone Marrow Transplantat, London WC1N 3JH, England

[5] Great Ormond St Hosp Sick Children, Dept Paediat Histopathol, London WC1N 3JH, England

[6] Great Ormond St Hosp Sick Children, Dept Radiol, London WC1N 3JH, England

来源：

MODERN PATHOLOGY | 2011年 / 24卷 / 12期

关键词：

bone marrow transplantation; graft-vs-host disease; pleuroparenchymal fibroelastosis; pneumothorax; STEM-CELL TRANSPLANTATION; IDIOPATHIC PNEUMONIA SYNDROME; VERSUS-HOST DISEASE; BRONCHIOLITIS-OBLITERANS; COMPLICATIONS; RECIPIENTS; PNEUMOTHORAX; SPECTRUM; FIBROSIS; AUTOPSY;

D O I：

10.1038/modpathol.2011.114

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

This study presents four patients who underwent bone marrow transplantation and subsequently developed pleuroparenchymal fibroelastosis, hitherto reported as an idiopathic condition. All presented clinically with pneumothorax and subpleural fibrosis on high-resolution computed tomography. In addition to the expected obliterative bronchiolitis, histopathology showed coexistent subpleural changes, and the relationship of pathology in multiple anatomic compartments in post bone marrow transplantation pulmonary disease is discussed. Modern Pathology (2011) 24, 1633-1639; doi:10.1038/modpathol.2011.114; published online 5 August 2011

引用

页码：1633 / 1639

页数：7

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