Structure and function of the uncoupling protein from brown adipose tissue

被引：302
作者：
Klingenberg, M [1 ]
Huang, SG [1 ]
机构：
[1] Univ Munich, Inst Phys Biochem, D-80336 Munich, Germany
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 1999年 / 1415卷 / 02期
关键词：
uncoupling protein; H+ transport; nucleotide binding; non-shivering thermogenesis; brown adipose tissue; structure-function relationship;
D O I：
10.1016/S0005-2736(98)00232-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：271 / 296
页数：26
相关论文
共 145 条
[1]   THE UNCOUPLING PROTEIN FROM BROWN FAT MITOCHONDRIA IS RELATED TO THE MITOCHONDRIAL ADP ATP CARRIER - ANALYSIS OF SEQUENCE HOMOLOGIES AND OF FOLDING OF THE PROTEIN IN THE MEMBRANE [J].
AQUILA, H ;
LINK, TA ;
KLINGENBERG, M .
EMBO JOURNAL, 1985, 4 (09) :2369-2376
[2]   SOLUTE CARRIERS INVOLVED IN ENERGY-TRANSFER OF MITOCHONDRIA FORM A HOMOLOGOUS PROTEIN FAMILY [J].
AQUILA, H ;
LINK, TA ;
KLINGENBERG, M .
FEBS LETTERS, 1987, 212 (01) :1-9
[3]   CYSTEINE RESIDUES ARE NOT ESSENTIAL FOR UNCOUPLING PROTEIN FUNCTION [J].
ARECHAGA, I ;
RAIMBAULT, S ;
PRIETO, S ;
LEVIMEYRUEIS, C ;
ZARAGOZA, P ;
MIROUX, B ;
RICQUIER, D ;
BOUILLAUD, F ;
RIAL, E .
BIOCHEMICAL JOURNAL, 1993, 296 :693-700
[4]   Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells [J].
Aubert, J ;
Champigny, O ;
SaintMarc, P ;
Negrel, R ;
Collins, S ;
Ricquier, D ;
Ailhaud, G .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 238 (02) :606-611
[5]   RABBIT BROWN ADIPOSE-TISSUE UNCOUPLING PROTEIN MESSENGER-RNA - USE OF ONLY ONE OF 2 POLYADENYLATION SIGNALS IN ITS PROCESSING [J].
BALOGH, AG ;
RIDLEY, RG ;
PATEL, HV ;
FREEMAN, KB .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 161 (01) :156-161
[6]   FUNCTIONAL EXPRESSION OF THE RAT BROWN ADIPOSE-TISSUE UNCOUPLING PROTEIN IN SACCHAROMYCES-CEREVISIAE [J].
BATHGATE, B ;
FREEBAIRN, EM ;
GREENLAND, AJ ;
REID, GA .
MOLECULAR MICROBIOLOGY, 1992, 6 (03) :363-370
[7]   STUDIES ON NOREPINEPHRINE-INDUCED EFFLUX OF FREE FATTY-ACID FROM HAMSTER BROWN-ADIPOSE-TISSUE CELLS [J].
BIEBER, LL ;
PETTERSSON, B ;
LINDBERG, O .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1975, 58 (02) :375-381
[8]   H+ transport by uncoupling protein (UCP-1) Is dependent on a histidine pair, absent in UCP-2 and UCP-3 [J].
Bienengraeber, M ;
Echtay, KS ;
Klingenberg, M .
BIOCHEMISTRY, 1998, 37 (01) :3-8
[9]   THE TRANSMEMBRANE ARRANGEMENT OF THE ADP/ATP CARRIER AS ELUCIDATED BY THE LYSINE REAGENT PYRIDOXAL 5-PHOSPHATE [J].
BOGNER, W ;
AQUILA, H ;
KLINGENBERG, M .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1986, 161 (03) :611-620
[10]   Uncoupling protein-3 expression in skeletal muscle and free fatty acids in obesity [J].
Boss, O ;
Bobbioni-Harsch, E ;
Assimacopoulos-Jeannet, F ;
Muzzin, P ;
Munger, R ;
Giacobino, JP ;
Golay, A .
LANCET, 1998, 351 (9120) :1933-1933
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