Cytotoxicity of AZ31B magnesium alloy covering with magnesium oxide

被引：0

作者：

Guo Lei ^{[1
]}

Liu Kui

Zhang Shiliang

Huang Jingjing ^{[2
]}

Tan Lili ^{[2
]}

Yang Ke ^{[2
]}

机构：

[1] China Med Univ, Affiliated Hosp 1, Dept Orthoped Surg, Shenyang 110001, Peoples R China

[2] Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China

来源：

RARE METAL MATERIALS AND ENGINEERING | 2008年 / 37卷 / 06期

关键词：

magnesium alloy; magnesium oxide; osteoblast; cytotoxicity;

D O I：

暂无

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The magnesium alloy AZ31B with magnesium oxide (MgO/AZ31B) film has been electrosynthesized by anodic oxidation technique at a constant current. The microstructure and cytotoxic effect of the magnesium alloys were detected; The effects of MgO/AZ31B magnesium alloy on the function of osteoblast were evaluated in vitro. The results show that the release and degradation processess of AZ31B magnesium alloy are efficiently delayed by coating with MgO, whereas the mutagenesis and hemolytic reactions of AZ31B magnesium alloy are degraded. It is shown that he MgO/AZ31B magnesium alloy does not affect the proliferation and the bone formation of osteoblast by the direct contact test in vitro. therefore; the MgO/AZ31B magnesium alloy would be a new degradable and biomedical material.

引用

页码：1027 / 1031

页数：5

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