Percutaneous Left Atrial Appendage Closure: Current Devices and Clinical Outcomes

被引:72
作者
Asmarats, Lluis [1 ]
Rodes-Cabau, Josep [1 ]
机构
[1] Laval Univ, Quebec Heart & Lung Inst, 2725 Ch St Foy, Quebec City, PQ G1V 4G5, Canada
关键词
anticoagulants; atrial appendage; atrial fibrillation; embolism; prevalence; COMBINED CATHETER ABLATION; AMPLATZER AMULET DEVICE; HIGH-RISK PATIENTS; WATCHMAN DEVICE; ORAL ANTICOAGULATION; STROKE PREVENTION; FOLLOW-UP; EMBOLIC PROTECTION; EARLY SAFETY; CARDIAC CT;
D O I
10.1161/CIRCINTERVENTIONS.117.005359
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chronic oral anticoagulation therapy is the standard therapy for preventing thromboembolic events in patients with atrial fibrillation. However, oral anticoagulation has been associated with an increased risk of bleeding events, and despite the improvements linked to the introduction of direct oral anticoagulants, more than one third of atrial fibrillation patients still remain untreated. Over the past decade, percutaneous left atrial appendage closure has emerged as a valid alternative to anticoagulation therapy for the prevention of stroke/systemic embolism in patients with atrial fibrillation. In this article, we provide an updated overview of current transcatheter left atrial appendage closure devices and review the results associated with left atrial appendage closure, focusing on procedural and late outcomes, and pointing to future directions.
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页数:16
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