New insights into the phylogenetic distribution and evolutionary origins of the septins

被引:83
作者
Nishihama, Ryuichi [1 ]
Onishi, Masayuki [1 ]
Pringle, John R. [1 ]
机构
[1] Stanford Univ, Dept Genet, Sch Med, Stanford, CA 94305 USA
关键词
brown algae; chlorophyte algae; ciliates; cytokinesis; green algae; guanine-nucleotide-binding proteins; SACCHAROMYCES-CEREVISIAE; FISSION YEAST; COILED COILS; PROTEIN; ORGANIZATION; SEQUENCE; REVEALS; COMPLEX;
D O I
10.1515/BC.2011.086
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Until recently, it had appeared that the septin family of proteins was restricted to the opisthokont eukaryotes (the fungi and animals and their close relatives the microsporidia and choanoflagellates). It has now become apparent that septins are also present in several other widely divergent eukaryotic lineages (chlorophyte algae, brown algae, and ciliates). This distribution and the details of the non-opisthokont septin sequences appear to require major revisions to hypotheses about the origins and early evolution of the septins.
引用
收藏
页码:681 / 687
页数:7
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