Controlled assembly of protein-nanoparticle composites through protein surface recognition

被引：90
作者：
Srivastava, S [1 ]
Verma, A [1 ]
Frankamp, BL [1 ]
Rotello, VM [1 ]
机构：
[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA
来源：
ADVANCED MATERIALS | 2005年 / 17卷 / 05期
关键词：
D O I：
10.1002/adma.200400776
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Controlled assembly of protein-nanoparticle composites through complementary protein surface recognition is demonstrated. Interaction of an unstable protein (chymotrypsin) with a gold nanoparticle results in close inter-particle spacing, while a stable protein (cytochrome C) that retains its structure upon binding produces a hybrid material with a larger interparticle distance (see Figure).
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收藏
页码：617 / +
页数：6
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