Progress of Nanomaterials-Based Photothermal Therapy for Oral Squamous Cell Carcinoma

被引：14

作者：

Niu, Qin ^{[1
,2
]}

Sun, Qiannan ^{[1
,2
]}

Bai, Rushui ^{[1
,2
]}

Zhang, Yunfan ^{[1
,2
]}

Zhuang, Zimeng ^{[1
,2
]}

Zhang, Xin ^{[1
,2
]}

Xin, Tianyi ^{[1
,2
]}

Chen, Si ^{[1
,2
]}

Han, Bing ^{[1
,2
]}

机构：

[1] Peking Univ, Sch & Hosp Stomatol, Dept Orthodont, Beijing 100081, Peoples R China

[2] Beijing Key Lab Digital Stomatol, Natl Engn Lab Digital & Mat Technol Stomatol, Beijing 100081, Peoples R China

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2022年 / 23卷 / 18期

基金：

国家重点研发计划; 中国国家自然科学基金; 中国博士后科学基金;

关键词：

oral squamous cell carcinoma; photothermal therapy; photothermal conversion agents; nanomaterials; drug delivery system; DRUG-DELIVERY SYSTEMS; CORE-SHELL NANOPARTICLES; GOLD-NANORODS; INDOCYANINE GREEN; CANCER-TREATMENT; POLYMERIC MICELLES; TONGUE CANCER; HYPERTHERMIA; CHEMO; NANOSTRUCTURES;

D O I：

10.3390/ijms231810428

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Oral squamous cell carcinoma (OSCC) is one of the top 15 most prevalent cancers worldwide. However, the current treatment models for OSCC (e.g., surgery, chemotherapy, radiotherapy, and combination therapy) present several limitations: damage to adjacent healthy tissue, possible recurrence, low efficiency, and severe side effects. In this context, nanomaterial-based photothermal therapy (PTT) has attracted extensive research attention. This paper reviews the latest progress in the application of biological nanomaterials for PTT in OSCC. We divide photothermal nanomaterials into four categories (noble metal nanomaterials, carbon-based nanomaterials, metal compounds, and organic nanomaterials) and introduce each category in detail. We also mention in detail the drug delivery systems for PTT of OSCC and briefly summarize the applications of hydrogels, liposomes, and micelles. Finally, we note the challenges faced by the clinical application of PTT nanomaterials and the possibility of further improvement, providing direction for the future research of PTT in OSCC treatment.

引用

页数：25

共 141 条

[81] Molybdenum Diphosphide Nanorods with Laser-Potentiated Peroxidase Catalytic/Mild-Photothermal Therapy of Oral Cancer [J].