Nano-biotechnology and its Innovative Perspective in Diabetes Management

被引:3
作者
Raval, Jigar [1 ]
Trivedi, Riddhi [1 ]
Suman, Sonali [2 ]
Kukrety, Arvind [2 ]
Prajapati, Prajesh [1 ]
机构
[1] Natl Forens Sci Univ, Sch Pharm, Gandhinagar 382007, Gujarat, India
[2] CDSCO, Ahmadabad 380003, Gujarat, India
关键词
Nano-biotechnology; diabetes; nanoparticles; metabolic disease; treatment; Insulin; ORAL INSULIN DELIVERY; IN-VIVO EVALUATION; SOLID LIPID NANOPARTICLES; TRANSDERMAL DELIVERY; DRUG-DELIVERY; VITRO CHARACTERIZATION; GOLD NANOPARTICLES; PROTEIN DELIVERY; GENE-THERAPY; HYDROGEL MICROPARTICLES;
D O I
10.2174/1389557521666210623164052
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The occurrence of the diabetes happens due to the irregular operation of glucose in the body, which is also known as glucose homeostasis, thus leading to metabolic changes in the body. The two stages whether hypoglycemia or hyperglycemia differentiates diabetes into various categories and brought new innovative management for the new routes of administration of these disease condition. Various bio-nanotechnologies which are coupled with nano particulates, polymers, Liposome, various gold plated and Solid Lipids Particulates regulate the transcellular transport, non specific cellular uptake, and paracellular transport, which leads to oral, transdermal, Pulmonary, buccal, Nasal, specific gene oriented administration to avoid the non patience compliance with the parental routes of administration. Phytochemicals have an emerging strategy for the future prospects of diabetes management.
引用
收藏
页码:89 / 114
页数:26
相关论文
共 194 条
  • [1] Abhilash M., 2010, International Journal of Pharma and Bio Sciences, V1, P1, DOI 10.5138/ijaps.2010.0976.1055.01001
  • [2] Aboubakar M, 1999, J BIOMED MATER RES, V47, P568, DOI 10.1002/(SICI)1097-4636(19991215)47:4<568::AID-JBM14>3.3.CO
  • [3] 2-O
  • [4] Encapsulation of insulin-cyclodextrin complex in PLGA microspheres: a new approach for prolonged pulmonary insulin delivery
    Aguiar, MMG
    Rodrigues, JM
    Cunha, AS
    [J]. JOURNAL OF MICROENCAPSULATION, 2004, 21 (05) : 553 - 564
  • [5] Ahmad A., 2012, J NANOMEDIC NANOTECH
  • [6] Amani M., 2012, RECENT ADV NOVEL DRU
  • [7] Amer Diabet Assoc, 2010, DIABETES CARE, V33, pS11, DOI [10.2337/dc10-S062, 10.2337/dc11-S011, 10.2337/dc10-S011, 10.2337/dc14-S081, 10.2337/dc13-S067, 10.2337/dc12-s064, 10.2337/dc11-S062, 10.2337/dc13-S011, 10.2337/dc12-s011]
  • [8] [Anonymous], 2010, WORLD APPL SCI J
  • [9] [Anonymous], 2008, Guidance for industry: diabetes mellitus-evaluating cardiovascular risk in new antidiabetic therapies to treat type 2 diabetes 2008
  • [10] [Anonymous], 2003, LIPOSOMES DRUG DELIV