Toll-like receptors and fungal infections: the role of TLR2, TLR4 and MyD88 in paracoccidioidomycosis

被引：58
|
作者：
Calich, Vera L. G. [1 ]
Pina, Adriana [1 ]
Felonato, Maira [1 ]
Bernardino, Simone [1 ]
Costa, Tania A. [1 ]
Loures, Flavio V. [1 ]
机构：
[1] Univ Sao Paulo, Inst Ciencias Biomed, Dept Imunol, BR-05508900 Sao Paulo, Brazil
来源：
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 2008年 / 53卷 / 01期
关键词：
toll-like receptors; fungal pathogens; paracoccidioidomycosis; TLR2; TLR4; MyD88;
D O I：
10.1111/j.1574-695X.2008.00378.x
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The aim of this minireview is to present a concise view of the most important pattern recognition receptors used by the innate immune system to sense and control pathogen growth into host tissues. A brief review of the role of Toll-like receptors (TLRs) in fungal infections followed by some recent results on the function of TLR4, TLR2 and the MyD88 adaptor molecule in the pathogenesis of paracoccidioidomycosis are presented.
引用
收藏
页码：1 / 7
页数：7
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