Toll-like receptors and fungal infections: the role of TLR2, TLR4 and MyD88 in paracoccidioidomycosis

被引：58

作者：

Calich, Vera L. G. ^{[1
]}

Pina, Adriana ^{[1
]}

Felonato, Maira ^{[1
]}

Bernardino, Simone ^{[1
]}

Costa, Tania A. ^{[1
]}

Loures, Flavio V. ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Ciencias Biomed, Dept Imunol, BR-05508900 Sao Paulo, Brazil

来源：

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 2008年 / 53卷 / 01期

关键词：

toll-like receptors; fungal pathogens; paracoccidioidomycosis; TLR2; TLR4; MyD88;

D O I：

10.1111/j.1574-695X.2008.00378.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The aim of this minireview is to present a concise view of the most important pattern recognition receptors used by the innate immune system to sense and control pathogen growth into host tissues. A brief review of the role of Toll-like receptors (TLRs) in fungal infections followed by some recent results on the function of TLR4, TLR2 and the MyD88 adaptor molecule in the pathogenesis of paracoccidioidomycosis are presented.

引用

页码：1 / 7

页数：7

共 50 条

[21] MyD88 Adaptor-Like Is Not Essential for TLR2 Signaling and Inhibits Signaling by TLR3
Kenny, Elaine F.
Talbot, Suzanne
Gong, Mei
Golenbock, Douglas T.
Bryant, Clare E.
O'Neill, Luke A. J.
JOURNAL OF IMMUNOLOGY, 2009, 183 (06) : 3642 - 3651
[22] Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia
Fan, Hongguang
Li, Litao
Zhang, Xiangjian
Liu, Ying
Yang, Chenhui
Yang, Yi
Yin, Jing
MEDIATORS OF INFLAMMATION, 2009, 2009
[23] Toll-like receptor (TLR2, TLR4) polymorphisms and their influence on the incidence of urinary tract infections in children with and without urinary tract malformation
Krakowska, Anna
Cedzynski, Maciej
Wosiak, Agnieszka
Swiechowski, Rafal
Krygier, Adrian
Tkaczyk, Marcin
Zeman, Krzysztof
CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY, 2022, 47 (03) : 260 - 266
[24] Toll-like receptor polymorphisms (TLR2 and TLR4) association with the risk of infectious complications in cardiac surgery patients
Zukowska, Agnieszka
Ciechanowicz, Andrzej
Kaczmarczyk, Mariusz
Brykczynski, Miroslaw
Zukowski, Maciej
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, 2023, 32 (01): : 57 - 63
[25] Differential expression of Toll-like receptor genes (TLR2 and TLR4) across different tissues of riverine buffalo
Dubey, P. K.
Goyal, S.
Namita
Mishra, S. K.
Gahlawat, S. K.
Kataria, R. S.
INDIAN JOURNAL OF ANIMAL SCIENCES, 2016, 86 (01) : 51 - 54
[26] Toll-like receptor polymorphisms (TLR2 and TLR4) association with the risk of infectious complications in cardiac surgery patients
Zukowska, Agnieszka
Ciechanowicz, Andrzej
Kaczmarczyk, Mariusz
Brykczynski, Miroslaw
Zukowski, Maciej
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, 2022,
[27] TLR2, TLR4 and the MyD88 Signaling Are Crucial For the In Vivo Generation and the Longevity of Long-Lived Antibody-Secreting Cells
Komegae, Evilin Naname
Grund, Lidiane Zito
Lopes-Ferreira, Monica
Lima, Carla
PLOS ONE, 2013, 8 (08):
[28] HMGB1 signals through toll-like receptor (TLR) 4 and TLR2
Yu, Man
Wang, Haichao
Ding, Aihao
Golenbock, Douglas T.
Latz, Eicke
Czura, Christopher J.
Fenton, Matthew J.
Tracey, Kevin J.
Yang, Huan
SHOCK, 2006, 26 (02): : 174 - 179
[29] The inflammatory microenvironment in epithelial ovarian cancer: a role for TLR4 and MyD88 and related proteins
Li, Zheng
Block, Matthew S.
Vierkant, Robert A.
Fogarty, Zachary C.
Winham, Stacey J.
Visscher, Daniel W.
Kalli, Kimberly R.
Wang, Chen
Goode, Ellen L.
TUMOR BIOLOGY, 2016, 37 (10) : 13279 - 13286
[30] Role of innate immune receptors TLR4 and TLR2 polymorphisms in systemic lupus erythematosus susceptibility
Elloumi, Nesrine
Tahri, Safa
Fakhfakh, Raouia
Abida, Olfa
Mahfoudh, Nadia
Hachicha, Hend
Marzouk, Sameh
Bahloul, Zouhir
Masmoudi, Hatem
ANNALS OF HUMAN GENETICS, 2022, 86 (03) : 137 - 144

← 1 2 3 4 5 →