Poly(glycerol sebacate) - a revolutionary biopolymer

被引：1
|
作者：
Jaafar, Israd H. [1 ]
Jedlicka, Sabrina S. [2 ]
Coulter, John P. [3 ]
机构：
[1] Utah Valley Univ, Mech Engn, 800 W Univ Pkwy, Orem, UT 84058 USA
[2] Lehigh Univ, Mat Sci & Engn, Bethlehem, PA 18015 USA
[3] Lehigh Univ, Mech Engn & Mech, Bethlehem, PA 18015 USA
来源：
PHYSICAL SCIENCES REVIEWS | 2021年
关键词：
biodegradable; biopolymer; elastomer; POLY GLYCEROL-SEBACATE; MESENCHYMAL STEM-CELLS; MECHANICAL-PROPERTIES; IN-VITRO; DEGRADATION; ELASTOMER; SCAFFOLDS; REGENERATION; MEMBRANES; BONE;
D O I：
10.1515/psr-2020-0071
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Novel materials possessing physical, mechanical, and chemical properties similar to those found in vivo provide a potential platform for building artificial microenvironments for tissue engineering applications. Poly(glycerol sebacate) is one such material. It has tunable mechanical properties within the range of common tissue, and favorable cell response without surface modification with adhesive ligands, and biodegradability. In this chapter, an overview of the material is presented, focusing on synthesis, characterization, microfabrication, use as a substrate in in vitro mammalian cell culture, and degradation characteristics.
引用
收藏
页码：363 / 383
页数：21
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