Assessment of diffusion-weighted imaging for characterizing focal liver lesions

被引:24
作者
Parsai, Arman [1 ]
Zerizer, Imene [2 ]
Roche, Oran [1 ]
Gkoutzios, Panos [3 ]
Miquel, Marc E. [1 ]
机构
[1] Barts Hlth NHS Trust, London E1 1BB, England
[2] Royal Marsden NHS Trust, London, England
[3] Guys & St Thomas NHS Trust, London, England
关键词
Diffusion-weighted imaging (DWI); Focal liver lesions; MRI; Malignant; Benign; MALIGNANT HEPATIC-LESIONS; MRI; ECHOPLANAR; BENIGN; MASSES; TUMORS;
D O I
10.1016/j.clinimag.2014.09.016
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
In 150 patients, 153 hepatic lesions (39 metastases, 27 hemangiomas, 26 hepatocellular carcinomas, 25 cysts, 15 adenomas, 8 focal nodular hyperplasias, 5 abscesses, 4 hamartomas, and 4 cholangiocarcinomas) were evaluated during a 24-month period. Apparent diffusion coefficient (ADC) values of benign lesions (1.994x10(-3)mm(2) s(-1)) were significantly higher than ADC values of malignant lesions (1.070x10(-3)mm(2) s(-1)). Mean ADC value for solid benign lesions (1.143x10(-3)mm(2) s(-1) +/- 0.214x10(-3)mm(2) s(-1)) was not significantly different from malignant lesions. ADC values did not allow differentiating malignant from benign solid lesions (area under the curve=0.61). ADC cutoff value threshold of 1.6x10(-3)mm(2) s(-1) yielded higher accuracy for differentiating benign from malignant lesions. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:278 / 284
页数:7
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