Ionic liquid-assisted synthesis of silica particles and their application in drug release

被引：22

作者：

Pang, Jianmei ^{[1
]}

Luan, Yuxia ^{[1
]}

Li, Feifei ^{[1
]}

Cai, Xiaoqing ^{[1
]}

Li, Zhonghao ^{[2
]}

机构：

[1] Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China

[2] Shandong Univ, Sch Mat Sci & Engn, Jinan 250061, Shandong, Peoples R China

来源：

MATERIALS LETTERS | 2010年 / 64卷 / 22期

基金：

中国国家自然科学基金;

关键词：

Nanomaterials; Microstructure; Ionic liquid; Silica; Drug release; MESOPOROUS SILICA; TEMPLATE;

D O I：

10.1016/j.matlet.2010.08.032

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Hollow and porous silica particles have been successfully prepared by a simple acid gelation route using the sodium silicate as the reactant in ionic liquid solution. 1-butyl-3-methylimidazolium tetrafluoroborate. The drug release behavior of the as-prepared porous silica particles is studied to reveal their potential use in drug delivery system. The current work for the synthesis of silica particles with the sodium silicate as the reactant in an ionic liquid might open new directions and opportunities to explore the application of ionic liquid in materials fields combining with the biomedical area (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：2509 / 2512

页数：4

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