Locomotion and its recovery after spinal injury

被引：109

作者：

Rossignol, S ^{[1
]}

机构：

[1] Univ Montreal, Fac Med, Ctr Rech Sci Neurol, Montreal, PQ H3C 3J7, Canada

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2000年 / 10卷 / 06期

关键词：

D O I：

10.1016/S0959-4388(00)00151-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Recent advances indicate not only that the spinal cord has great potential for locomotor recovery after lesion but also that locomotor training can optimise this recovery through some form of 'learning'. Improvement of residual function can also be achieved through the use of various drugs and treatments such as spinal grafts. In spinal-cord-injured humans, a number of recent studies have allowed an objective quantification of the improvement of locomotion through various forms of training and stimulation.

引用

页码：708 / 716

页数：9

共 63 条

[31]

HODGSON JA, 1994, MED SCI SPORT EXER, V26, P1491

[32] A therapeutic vaccine approach to stimulate axon regeneration in the adult mammalian spinal cord [J].

Huang, DW ;

McKerracher, L ;

Braun, PE ;

David, S .

NEURON, 1999, 24 (03) :639-647

[33] Effects of bilateral lesions of the dorsolateral funiculi and dorsal columns at the level of the low thoracic spinal cord on the control of locomotion in the adult cat .1. Treadmill walking [J].

Jiang, W ;

Drew, T .

JOURNAL OF NEUROPHYSIOLOGY, 1996, 76 (02) :849-866

[34] An in vitro functionally mature mouse spinal cord preparation for the study of spinal motor networks [J].

Jiang, ZY ;

Carlin, KP ;

Brownstone, RM .

BRAIN RESEARCH, 1999, 816 (02) :493-499

[35]

Kalb RG, 2000, CONT NEUROS, pV

[36] Distribution of central pattern generators for rhythmic motor outputs in the spinal cord of limbed vertebrates [J].

Kiehn, O ;

Kjaerulff, O .

NEURONAL MECHANISMS FOR GENERATING LOCOMOTOR ACTIVITY, 1998, 860 :110-129

[37]

Kim M, 1997, J NEUROSCI, V17, P8213

[38]

Ladouceur M, 2000, SCAND J REHABIL MED, V32, P28

[39] EFFECTS OF TRAINING ON THE RECOVERY OF FULL-WEIGHT-BEARING STEPPING IN THE ADULT SPINAL CAT [J].

LOVELY, RG ;

GREGOR, RJ ;

ROY, RR ;

EDGERTON, VR .

EXPERIMENTAL NEUROLOGY, 1986, 92 (02) :421-435

[40] Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord [J].

McDonald, JW ;

Liu, XZ ;

Qu, Y ;

Liu, S ;

Mickey, SK ;

Turetsky, D ;

Gottlieb, DI ;

Choi, DW .

NATURE MEDICINE, 1999, 5 (12) :1410-1412

← 1 2 3 4 5 6 7 →