Epidemiology of post-hemorrhagic ventricular dilatation in very preterm infants

被引：4
作者：
Afifi, Jehier [1 ,2 ]
Shah, Prakesh S. [3 ,4 ,5 ]
Ye, Xiang Y. [3 ]
Shah, Vibhuti [4 ,5 ]
Piedboeuf, Bruno [6 ]
Barrington, Keith [7 ]
Kelly, Edmond [4 ,5 ]
El-Naggar, Walid [1 ,2 ]
机构：
[1] IWK Hlth Ctr, Dept Pediat, Halifax, NS, Canada
[2] Dalhousie Univ, Halifax, NS, Canada
[3] Mt Sinai Hosp, Maternal Infant Care Res Ctr, Toronto, ON, Canada
[4] Mt Sinai Hosp, Dept Pediat, Toronto, ON, Canada
[5] Univ Toronto, Toronto, ON, Canada
[6] Univ Laval, CHU Quebec, Dept Pediat, Quebec City, PQ, Canada
[7] CHU St Justine, Dept Pediat, Quebec City, PQ, Canada
来源：
JOURNAL OF PERINATOLOGY | 2022年 / 42卷 / 10期
基金：
加拿大健康研究院;
关键词：
LOW-BIRTH-WEIGHT; SEVERE INTRAVENTRICULAR HEMORRHAGE; LATERAL VENTRICLES; PREMATURE-INFANTS; CEREBROSPINAL-FLUID; NEONATAL OUTCOMES; RISK-FACTORS; HYDROCEPHALUS; MANAGEMENT; DRAINAGE;
D O I：
10.1038/s41372-022-01483-6
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective To describe the incidence, trends, management's variability and short-term outcomes of preterm infants with severe post-hemorrhagic ventricular dilatation (sPHVD). Methods We reviewed infants <33 weeks' gestation who had PHVD and were admitted to the Canadian Neonatal Network between 2010 and 2018. We compared perinatal characteristics and short-term outcomes between those with sPHVD and those with mild/moderate PHVD and those with and without ventriculo-peritoneal (VP) shunt. Results Of 29,417 infants, 2439 (8%) had PHVD; rate increased from 7.3% in 2010 to 9.6% in 2018 (P = 0.005). Among infants with PHVD, sPHVD (19%) and VP shunt (29%) rates varied significantly across Canadian centers and between geographic regions (P < 0.01 and P = 0.0002). On multivariable analysis, sPHVD was associated with greater mortality, seizures and meningitis compared to mild/moderate PHVD. Conclusions Significant variability in sPHVD and VP shunt rates exists between centers and regions in Canada. sPHVD was associated with increased mortality and morbidities.
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收藏
页码：1392 / 1399
页数：8
相关论文
共 49 条
[1]   Neurodevelopmental outcome of extremely low birth weight infants with posthemorrhagic hydrocephalus requiring shunt insertion [J].
Adams-Chapman, Ira ;
Hansen, Nellie I. ;
Stoll, Barbara J. ;
Higgins, Rose .
PEDIATRICS, 2008, 121 (05) :E1167-E1177
[2]   Intraventricular Hemorrhage and Post Hemorrhagic Hydrocephalus among Very-Low-Birth-Weight Infants in Korea [J].
Ahn, So Yoon ;
Shim, So-Yeon ;
Sung, In Kyung .
JOURNAL OF KOREAN MEDICAL SCIENCE, 2015, 30 :S52-S58
[3]   Survival and Morbidity of Preterm Children Born at 22 Through 34 Weeks' Gestation in France in 2011 Results of the EPIPAGE-2 Cohort Study [J].
Ancel, Pierre-Yves ;
Goffinet, Francois .
JAMA PEDIATRICS, 2015, 169 (03) :230-238
[4]  
[Anonymous], 2014, Canadian organ replacement register annual report: Treatment of end-stage organ failure in Canada, 2004 to 2013, P1
[5]   Timing of external ventricular drainage and neurodevelopmental outcome in preterm infants with posthemorrhagic hydrocephalus [J].
Bassan, Haim ;
Eshel, Rina ;
Golan, Inbal ;
Kohelet, David ;
Ben Sira, Liat ;
Mandel, Dror ;
Levi, Loren ;
Constantini, Shlomi ;
Beni-Adani, Liana .
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2012, 16 (06) :662-670
[6]   European perspective on the diagnosis and treatment of posthaemorrhagic ventricular dilatation [J].
Brouwer, A. J. ;
Brouwer, M. J. ;
Groenendaal, F. ;
Benders, M. J. N. L. ;
Whitelaw, A. ;
de Vries, L. S. .
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 2012, 97 (01) :F50-F55
[7]   Neurodevelopmental outcome of preterm infants with severe intraventricular hemorrhage and therapy for post-hemorrhagic ventricular dilatation [J].
Brouwer, Annemieke ;
Groenendaal, Floris ;
van Haastert, Inge-Lot ;
Rademaker, Karin ;
Hanlo, Patrick ;
de Vries, Linda .
JOURNAL OF PEDIATRICS, 2008, 152 (05) :648-654
[8]   Ultrasound measurements of the lateral ventricles in neonates: why, how and when? A systematic review [J].
Brouwer, Margaretha J. ;
de Vries, Linda S. ;
Pistorius, Lou ;
Rademaker, Karin J. ;
Groenendaal, Floris ;
Benders, Manon J. N. L. .
ACTA PAEDIATRICA, 2010, 99 (09) :1298-1306
[9]   Surgical management of hydrocephalus secondary to intraventricular hemorrhage in the preterm infant [J].
Christian, Eisha A. ;
Melamed, Edward F. ;
Peck, Edwin ;
Krieger, Mark D. ;
McComb, J. Gordon .
JOURNAL OF NEUROSURGERY-PEDIATRICS, 2016, 17 (03) :278-284
[10]   Trends in hospitalization of preterm infants with intraventricular hemorrhage and hydrocephalus in the United States, 2000-2010 [J].
Christian, Eisha A. ;
Jin, Diana L. ;
Attenello, Frank ;
Wen, Timothy ;
Cen, Steven ;
Mack, William J. ;
Krieger, Mark D. ;
McComb, J. Gordon .
JOURNAL OF NEUROSURGERY-PEDIATRICS, 2016, 17 (03) :260-269
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