The role of ECVAM in promoting the regulatory acceptance of alternative methods in the European Union

被引：24

作者：

Worth, AP ^{[1
]}

Balls, M ^{[1
]}

机构：

[1] Commiss European Communities, Joint Res Ctr, Inst Hlth & Consumer Protect, ECVAM, I-21020 Ispra, VA, Italy

来源：

ATLA-ALTERNATIVES TO LABORATORY ANIMALS | 2001年 / 29卷 / 05期

关键词：

validation; alternative method; ECVAM; ESAC; regulatory acceptance;

D O I：

10.1177/026119290102900512

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The roles played by the European Centre for the Validation of Alternative Methods (ECVAM) and its advisory committee, the ECVAM Scientific Advisory Committee (ESAC), in the evolution of alternative methods are described. Particular emphasis is given to the process by which ECVAM and the ESAC assess the scientific validities of alternative methods, and, in appropriate cases, initiate the progression of scientifically validated methods toward regulatory acceptance.

引用

页码：525 / 535

页数：11

共 43 条

[1]

[Anonymous], [No title captured]

[2]

Balls M, 1995, ATLA-ALTERN LAB ANIM, V23, P884

[3] The validation and acceptance of alternatives to animal testing [J].

Balls, M ;

Fentem, JH .

TOXICOLOGY IN VITRO, 1999, 13 (4-5) :837-846

[4]

Balls M, 1997, ATLA-ALTERN LAB ANIM, V25, P33

[5]

BALLS M, 1995, ATLA-ALTERN LAB ANIM, V23, P129

[6]

Balls M, 1997, ATLA-ALTERN LAB ANIM, V25, P483

[7] Defining the role of ECVAM in the development, validation and acceptance of alternative tests and testing strategies [J].

Balls, M .

TOXICOLOGY IN VITRO, 1995, 9 (06) :863-869

[8] The ECVAM international validation study on in vitro tests for skin corrosivity. 1. Selection and distribution of the test chemicals [J].

Barratt, MD ;

Brantom, PG ;

Fentem, JH ;

Gerner, I ;

Walker, AP ;

Worth, AP .

TOXICOLOGY IN VITRO, 1998, 12 (04) :471-482

[9]

BASKETTER DA, 1999, FOOD CHEM TOXICOL, V37, P1

[10] Establishment of an in vitro reporter gene assay for developmental cardiac toxicity [J].

Bremer, S ;

Worth, AP ;

Paparella, M ;

Bigot, K ;

Kolossov, E ;

Fleischmann, BK ;

Hescheler, J ;

Balls, M .

TOXICOLOGY IN VITRO, 2001, 15 (03) :215-223

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