A label-free thrombin binding aptamer as a probe for highly sensitive and selective detection of lead(II) ions by a resonance Rayleigh scattering method

被引:52
作者
Fu, Xiao Bei [1 ]
Qu, Fei [1 ]
Li, Nian Bing [1 ]
Luo, Hong Qun [1 ]
机构
[1] Southwest Univ, Sch Chem & Chem Engn, Educ Minist, Key Lab Luminescence & Real Time Anal, Chongqing 400715, Peoples R China
基金
中国国家自然科学基金;
关键词
LIGHT-SCATTERING; AMINOGLYCOSIDE ANTIBIOTICS; ASSOCIATION NANOPARTICLES; FLUORESCENCE DETECTION; COLORIMETRIC DETECTION; GOLD NANOPARTICLES; SPECTRAL DETECTION; CATALYTIC BEACONS; MODIFIED NANOGOLD; DNAZYME SENSOR;
D O I
10.1039/c2an15980e
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The binding of lead(II) ions with unusually high affinity to a thrombin binding aptamer resulted in an enhancement of resonance Rayleigh scattering (RRS). A simple, sensitive, and selective assay for the direct determination of trace amounts of Pb2+ on the basis of RRS has been proposed.
引用
收藏
页码:1097 / 1099
页数:3
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