A label-free thrombin binding aptamer as a probe for highly sensitive and selective detection of lead(II) ions by a resonance Rayleigh scattering method

被引：52

作者：

Fu, Xiao Bei ^{[1
]}

Qu, Fei ^{[1
]}

Li, Nian Bing ^{[1
]}

Luo, Hong Qun ^{[1
]}

机构：

[1] Southwest Univ, Sch Chem & Chem Engn, Educ Minist, Key Lab Luminescence & Real Time Anal, Chongqing 400715, Peoples R China

来源：

ANALYST | 2012年 / 137卷 / 05期

基金：

中国国家自然科学基金;

关键词：

LIGHT-SCATTERING; AMINOGLYCOSIDE ANTIBIOTICS; ASSOCIATION NANOPARTICLES; FLUORESCENCE DETECTION; COLORIMETRIC DETECTION; GOLD NANOPARTICLES; SPECTRAL DETECTION; CATALYTIC BEACONS; MODIFIED NANOGOLD; DNAZYME SENSOR;

D O I：

10.1039/c2an15980e

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The binding of lead(II) ions with unusually high affinity to a thrombin binding aptamer resulted in an enhancement of resonance Rayleigh scattering (RRS). A simple, sensitive, and selective assay for the direct determination of trace amounts of Pb2+ on the basis of RRS has been proposed.

引用

页码：1097 / 1099

页数：3

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