Use of yttrium-90 microspheres (TheraSphere®) in a patient with unresectable hepatocellular carcinoma leading to liver transplantation:: A case report

被引:39
作者
Kulik, LM
Mulcahy, MF
Hunter, RD
Nemcek, AA
Abecassis, MM
Salem, R
机构
[1] Northwestern Mem Hosp, Dept Hepatol, Chicago, IL USA
[2] Northwestern Univ, Dept Hematol & Oncol, Robert H Lurie Comprehens Canc Ctr, Chicago, IL USA
[3] Northwestern Univ, Dept Radiol, Chicago, IL USA
[4] MDS Pharma Serv, King Of Prussia, PA USA
[5] Northwestern Mem Hosp, Div Transplant Surg, Robert H Lurie Comprehens Canc Ctr, Chicago, IL USA
关键词
D O I
10.1002/lt.20514
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Prior to therapy, model for end stage liver disease (MELD) scoring, diagnostic imaging and tumor staging were performed in a patient with T3 HCC. The patient received an orthotopic liver transplant (OLT) 42 days after treatment. The explant specimen showed complete necrosis of the target tumor. Follow-up of this patient has demonstrated no evidence of recurrence. There was no life threatening or fatal adverse experiences related to treatment. This case report documents the natural course, history and outcome of a patient treated with yttrium-90 for unresectable HCC. The patient was downstaged from T3 to T2 and was subsequently transplanted.
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页码:1127 / 1131
页数:5
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