Successful treatment of comorbid obsessive-compulsive disorder with aripiprazole in three patients with bipolar disorder

Data on the efficacy of aripiprazole in obsessive compulsive disorder (OCD), compared to data on the efficacy of other atypical antipsychotics, are inadequate. This report presents the successful treatment of concurrent OCD with aripiprazole in three patients with bipolar disorder (BD). Assessments performed with the Yale Brown Obsessive Compulsive Scale revealed significant reductions in OCD symptoms. Aripiprazole may be a beneficial psychotropic agent for the treatment of BD and OCD comorbidity, which is an important problem in clinical practice. (C) 2010 Elsevier Inc. All rights reserved.