Eco-friendly polyethylene glycol-400: a rapid and efficient recyclable reaction medium for the synthesis of thiazole derivatives

被引：26

作者：

Dawane, Bhaskar S. ^{[1
]}

Shaikh, Baseer M. ^{[1
]}

Khandare, Namdev T. ^{[1
]}

Kamble, Vinod T. ^{[2
]}

Chobe, Santosh S. ^{[1
]}

Konda, Shankaraiah G. ^{[1
]}

机构：

[1] Yeshwant Mahavidyalaya, Dept Chem, Organ Res Lab, Nanded 431602, Maharashtra, India

[2] Swami Ramanand Teerth Marathwada Univ, Sch Chem Sci, Organ Res Lab, Nanded 431606, Maharashtra, India

来源：

GREEN CHEMISTRY LETTERS AND REVIEWS | 2010年 / 3卷 / 03期

关键词：

polyethylene glycol; alpha-haloketones; thiourea; substituted acetophenones; thiazole derivatives; POLY(ETHYLENE GLYCOL); ALZHEIMER-DISEASE; INHIBITORS; SOLVENT; SERIES; SYSTEM; DRUGS;

D O I：

10.1080/17518251003709506

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient and convenient procedure for the synthesis of thiazole derivatives from alpha-haloketone, thiourea and substituted acetophenones using polyethylene glycol-400 as a green and recyclable solvent is described. Significant rate enhancement and improved yields have been observed.

引用

页码：205 / 208

页数：4

共 19 条

[1] PHENETHYLTHIAZOLETHIOUREA (PETT) COMPOUNDS, A NEW CLASS OF HIV-1 REVERSE-TRANSCRIPTASE INHIBITORS .1. SYNTHESIS AND BASIC STRUCTURE-ACTIVITY RELATIONSHIP STUDIES OF PETT ANALOGS [J].

BELL, FW ;

CANTRELL, AS ;

HOGBERG, M ;

JASKUNAS, SR ;

JOHANSSON, NG ;

JORDAN, CL ;

KINNICK, MD ;

LIND, P ;

MORIN, JM ;

NOREEN, R ;

OBERG, B ;

PALKOWITZ, JA ;

PARRISH, CA ;

PRANC, P ;

SAHLBERG, C ;

TERNANSKY, RJ ;

VASILEFF, RT ;

VRANG, L ;

WEST, SJ ;

ZHANG, H ;

ZHOU, XX .

JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (25) :4929-4936

[2]

Cacabelos R, 2000, DRUG TODAY, V36, P415

[3] Non-Cholinergic Pharmacotherapy Approaches to the Future Treatment of Alzheimer's Disease [J].

Castro, Ana ;

Conde, Santiago ;

Isabel Rodriguez-Franco, M. ;

Martinez, Ana .

MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2002, 2 (01) :37-50

[4] Polyethylene glycol and solutions of polyethylene glycol as green reaction media [J].

Chen, J ;

Spear, SK ;

Huddleston, JG ;

Rogers, RD .

GREEN CHEMISTRY, 2005, 7 (02) :64-82

[5] 4-HYDROXY-3-QUINOLINECARBOXAMIDES WITH ANTIARTHRITIC AND ANALGESIC ACTIVITIES [J].

CLEMENCE, F ;

LEMARTRET, O ;

DELEVALLEE, F ;

BENZONI, J ;

JOUANEN, A ;

JOUQUEY, S ;

MOUREN, M ;

DERAEDT, R .

JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (07) :1453-1462

[6] THE REACTION OF KETONES WITH HALOGENS AND THIOUREA [J].

DODSON, RM ;

KING, LC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1945, 67 (12) :2242-2243

[7] N-(4-SUBSTITUTED-THIAZOLYL)OXAMIC ACID-DERIVATIVES, A NEW SERIES OF POTENT, ORALLY ACTIVE ANTIALLERGY AGENTS [J].

HARGRAVE, KD ;

HESS, FK ;

OLIVER, JT .

JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (08) :1158-1163

[8] Liquid poly(ethylene glycol) and supercritical carbon dioxide: A benign biphasic solvent system for use and recycling of homogeneous catalysts [J].

Heldebrant, DJ ;

Jessop, PG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (19) :5600-5601

[9] 4-(1,2,5,6-TETRAHYDRO-1-ALKYL-3-PYRIDINYL)-2-THIAZOLAMINES - A NOVEL CLASS OF COMPOUNDS WITH CENTRAL DOPAMINE AGONIST PROPERTIES [J].

JAEN, JC ;

WISE, LD ;

CAPRATHE, BW ;

TECLE, H ;

BERGMEIER, S ;

HUMBLET, CC ;

HEFFNER, TG ;

MELTZER, LT ;

PUGSLEY, TA .

JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (01) :311-317

[10] THE REACTION OF KETONES WITH IODINE AND THIOUREA [J].

KING, LC ;

HLAVACEK, RJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1950, 72 (08) :3722-3725

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