Multi-Scale Multivariate Models for Small Area Health Survey Data: A Chilean Example

被引:1
作者
Lawson, Andrew [1 ]
Schritz, Anna [2 ]
Villarroel, Luis [3 ]
Aguayo, Gloria A. [2 ]
机构
[1] Med Univ South Carolina, Dept Publ Hlth Sci, Charleston, SC 29466 USA
[2] Luxembourg Inst Hlth, 1A-B Rue Thomas Edison, L-1445 Luxembourg, Luxembourg
[3] Pontificia Univ Catolica Chile, Sch Med, Publ Hlth Dept, Diagonal Paraguay 362, Santiago 8330077, Chile
关键词
Bayesian modeling; multivariate; multi-scale; spatial correlation; sample weights; CANCER;
D O I
10.3390/ijerph17051682
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Background: We propose a general approach to the analysis of multivariate health outcome data where geo-coding at different spatial scales is available. We propose multiscale joint models which address the links between individual outcomes and also allow for correlation between areas. The models are highly novel in that they exploit survey data to provide multiscale estimates of the prevalences in small areas for a range of disease outcomes. Results The models incorporate both disease specific, and common disease spatially structured components. The multiple scales envisaged is where individual survey data is used to model regional prevalences or risks at an aggregate scale. This approach involves the use of survey weights as predictors within our Bayesian multivariate models. Missingness has to be addressed within these models and we use predictive inference which exploits the correlation between diseases to provide estimates of missing prevalances. The Case study we examine is from the National Health Survey of Chile where geocoding to Province level is available. In that survey, diabetes, Hypertension, obesity and elevated low-density cholesterol (LDL) are available but differential missingness requires that aggregation of estimates and also the assumption of smoothed sampling weights at the aggregate level. Conclusions: The methodology proposed is highly novel and flexibly handles multiple disease outcomes at individual and aggregated levels (i.e., multiscale joint models). The missingness mechanism adopted provides realistic estimates for inclusion in the aggregate model at Provincia level. The spatial structure of four diseases within Provincias has marked spatial differentiation, with diabetes and hypertension strongly clustered in central Provincias and obesity and LDL more clustered in the southern areas.
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页数:20
相关论文
共 24 条
[1]  
[Anonymous], 2012, BUGS BOOK PRACTICAL
[2]  
Aregay M, 2017, SPAT SPATIO-TEMPORAL, V22, P39, DOI 10.1016/j.sste.2017.06.001
[3]   Bayesian multi-scale modeling for aggregated disease mapping data [J].
Aregay, Mehreteab ;
Lawson, Andrew B. ;
Faes, Christel ;
Kirby, Russell S. .
STATISTICAL METHODS IN MEDICAL RESEARCH, 2017, 26 (06) :2726-2742
[4]   BAYESIAN IMAGE-RESTORATION, WITH 2 APPLICATIONS IN SPATIAL STATISTICS [J].
BESAG, J ;
YORK, J ;
MOLLIE, A .
ANNALS OF THE INSTITUTE OF STATISTICAL MATHEMATICS, 1991, 43 (01) :1-20
[5]   General methods for monitoring convergence of iterative simulations [J].
Brooks, SP ;
Gelman, A .
JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS, 1998, 7 (04) :434-455
[6]   The use of sampling weights in Bayesian hierarchical models for small area estimation [J].
Chen, Cici ;
Wakefield, Jon ;
Lumely, Thomas .
SPATIAL AND SPATIO-TEMPORAL EPIDEMIOLOGY, 2014, 11 :33-43
[7]  
Clark-Nunez X, 2017, COMPENDIO ESTADISTIC
[8]  
Gelman A., 1992, Stat. Sci., V7, P457, DOI [10.1214/ss/1177011136, DOI 10.1214/SS/1177011136]
[9]  
Kolaczyk ED, 2001, GEOGR ANAL, V33, P95
[10]  
Lawson, 2018, BAYESIAN DIS MAPPING