Cardiovascular dysfunction in infants with neonatal encephalopathy

被引：57

作者：

Armstrong, Katey ^{[1
,2
,3
]}

Franklin, Orla ^{[2
]}

Sweetman, Deirdre ^{[1
,3
]}

Molloy, Eleanor J. ^{[1
,3
,4
,5
]}

机构：

[1] Natl Matern Hosp, Dept Paediat, Dublin 2, Ireland

[2] Our Ladys Childrens Hosp, Dept Paediat Cardiol, Dublin, Ireland

[3] Natl Childrens Res Ctr, Dublin, Ireland

[4] Royal Coll Surgeons Ireland, Dublin 2, Ireland

[5] Univ Coll Dublin, UCD Sch Med & Med Sci, Dublin 2, Ireland

来源：

ARCHIVES OF DISEASE IN CHILDHOOD | 2012年 / 97卷 / 04期

关键词：

HYPOXIC-ISCHEMIC ENCEPHALOPATHY; PERSISTENT PULMONARY-HYPERTENSION; ACUTE MYOCARDIAL-INFARCTION; WHOLE-BODY HYPOTHERMIA; EMBRYONIC STEM-CELLS; CARDIAC TROPONIN-T; NATRIURETIC PEPTIDE; ELECTROCARDIOGRAPHIC CHANGES; NORMAL VALUES; PERFORMANCE;

D O I：

10.1136/adc.2011.214205

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Severe perinatal asphyxia with hypoxic ischaemic encephalopathy occurs in approximately 1-2/1000 live births and is an important cause of cerebral palsy and associated neurological disabilities in children. Multiorgan dysfunction commonly occurs as part of the asphyxial episode, with cardiovascular dysfunction occurring in up to a third of infants. This narrative paper attempts to review the literature on the importance of early recognition of cardiac dysfunction using echocardiography and biomarkers such as troponin and brain type natriuretic peptide. These tools may allow accurate assessment of cardiac dysfunction and guide therapy to improve outcome.

引用

页码：372 / 375

页数：4

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