Epidemiology, pathophysiology, diagnosis, and management of intracranial artery dissection

被引：324

作者：

Debette, Stephanie ^{[1
,2
]}

Compter, Annette ^{[3
]}

Labeyrie, Marc-Antoine ^{[4
]}

Uyttenboogaart, Maarten ^{[5
,6
]}

Metso, Tina M. ^{[7
]}

Majersik, Jennifer J. ^{[8
]}

Goeggel-Simonetti, Barbara ^{[9
,10
]}

Engelter, Stefan T. ^{[11
,12
,13
]}

Pezzini, Alessandro ^{[14
]}

Bijlenga, Philippe ^{[15
]}

Southerland, Andrew M. ^{[16
,17
]}

Naggara, Olivier ^{[18
]}

Bejot, Yannick ^{[19
]}

Cole, John W. ^{[20
]}

Ducros, Anne ^{[21
]}

Giacalone, Giacomo ^{[22
]}

Schilling, Sabrina ^{[2
]}

Reiner, Peggy ^{[1
]}

Sarikaya, Hakan ^{[9
,10
,23
]}

Welleweerd, Janna C. ^{[24
]}

Kappelle, L. Jaap ^{[3
]}

de Borst, Gert Jan ^{[24
]}

Bonati, Leo H. ^{[11
,12
]}

Jung, Simon ^{[9
,10
]}

Thijs, Vincent ^{[25
,26
,27
]}

Martin, Juan J. ^{[28
]}

Brandt, Tobias ^{[29
]}

Grand-Ginsbach, Caspar ^{[30
]}

Kloss, Manja ^{[30
]}

Mizutani, Tohru ^{[31
]}

Minematsu, Kazuo ^{[32
]}

Meschia, James F. ^{[33
]}

Pereira, Vitor M. ^{[34
,35
]}

Bersano, Anna ^{[36
]}

Touze, Emmanuel ^{[37
]}

Lyrer, Philippe A. ^{[11
,12
]}

Leys, Didier ^{[38
]}

Chabriat, Hugues ^{[1
]}

Markus, Hugh S. ^{[39
]}

Worrall, Bradford B. ^{[16
,17
]}

Chabrier, Stephane ^{[40
,41
]}

Baumgartner, Ralph ^{[42
]}

Stapf, Christian ^{[1
]}

Tatlisumak, Turgut ^{[7
]}

Arnold, Marcel ^{[9
,10
]}

Bousser, Marie-Germaine ^{[1
]}

机构：

[1] Univ Paris 07, Lariboisiere Hosp, Dept Neurol, DHU Neurovasc Sorbonne Paris Cite, Paris, France

[2] Bordeaux Univ, INSERM U897, F-33000 Bordeaux, France

[3] Univ Med Ctr Utrecht, Brain Ctr Rudolf Magnus, Dept Neurol & Neurosurg, Utrecht, Netherlands

[4] Univ Paris 07, Lariboisiere Hosp, Dept Neuroradiol, DHU Neurovasc Sorbonne Paris Cite, Paris, France

[5] Univ Groningen, Univ Med Ctr Groningen, Dept Neurol, NL-9713 AV Groningen, Netherlands

[6] Univ Groningen, Univ Med Ctr Groningen, Dept Radiol, NL-9713 AV Groningen, Netherlands

[7] Univ Helsinki, Cent Hosp, Dept Neurol, Helsinki, Finland

[8] Univ Utah, Dept Neurol, Salt Lake City, UT USA

[9] Univ Hosp Bern, Inselspital, Dept Neurol, CH-3010 Bern, Switzerland

[10] Univ Bern, Bern, Switzerland

[11] Univ Basel Hosp, Dept Neurol, CH-4031 Basel, Switzerland

[12] Univ Basel Hosp, Stroke Ctr, CH-4031 Basel, Switzerland

[13] Felix Platter Hosp, Univ Ctr Med Aging & Rehabil Basel, Neurorehabil Unit, Basel, Switzerland

[14] Brescia Univ Hosp, Neurol Clin, Dept Clin & Expt Sci, Brescia, Italy

[15] Univ Geneva, Med Ctr, Fac Med, Dept Clin Neurosci,Neurosurg Div, CH-1211 Geneva, Switzerland

[16] Univ Virginia, Dept Neurol, Charlottesville, VA USA

[17] Univ Virginia, Dept Publ Hlth Sci, Charlottesville, VA USA

[18] Univ Paris 05, Ctr Hosp St Anne, DHU Neurovasc Paris Sorbonne, Dept Neuroradiol,INSERM UMR 894, Paris, France

[19] Dijon Univ Hosp, Dept Neurol, Dijon, France

[20] Univ Maryland, Sch Med, Dept Neurol, Baltimore, MD 21201 USA

[21] Univ Montpellier I, Gui de Chauliac Hosp, Dept Neurol, Montpellier, France

[22] IRCCS San Raffaele, Inst Expt Neurol INSPE, Dept Neurol, Milan, Italy

[23] Univ Zurich Hosp, Dept Neurol, CH-8091 Zurich, Switzerland

[24] Univ Med Ctr Utrecht, Dept Vasc Surg, Utrecht, Netherlands

[25] Univ Leuven, KU Leuven, Neurobiol Lab, Dept Neurosci,Expt Neurol, Leuven, Belgium

[26] VIB, Vesalius Res Ctr, Leuven, Belgium

[27] Univ Hosp Leuven, Dept Neurol, Leuven, Belgium

[28] Sanatorio Allende, Dept Neurol, Cordoba, Argentina

[29] Kliniken Schmieder, Clin Neurol Rehabil, Heidelberg, Germany

[30] Heidelberg Univ, Dept Neurol, Heidelberg, Germany

[31] Showa Univ, Dept Neurosurg, Tokyo, Japan

[32] Natl Cerebral & Cardiovasc Ctr, Dept Cerebrovasc Med, Suita, Osaka, Japan

[33] Mayo Clin, Dept Neurol, Jacksonville, FL 32224 USA

[34] Univ Hlth Network, Toronto Western Hosp, Dept Med Imaging, Div Neuroradiol, Toronto, ON, Canada

[35] Univ Hlth Network, Toronto Western Hosp, Dept Surg, Div Neurosurg, Toronto, ON, Canada

[36] IRCCS Fdn C Besta Neurol Inst, Cerebrovasc Dis Unit, Milan, Italy

[37] Univ Caen Basse Normandie, Inserm U919, Dept Neurol, CHU Cote Nacre, Caen, France

[38] Lille Univ Hosp, Dept Neurol, Lille, France

[39] Univ Cambridge, Dept Clin Neurosci, Cambridge, England

[40] St Etienne Univ Hosp, French Ctr Paediat Stroke, St Etienne, France

[41] St Etienne Univ Hosp, EA3065, St Etienne, France

[42] Clin Hirslanden Zurich, NeuroCtr, Zurich, Switzerland

来源：

LANCET NEUROLOGY | 2015年 / 14卷 / 06期

基金：

瑞士国家科学基金会; 美国国家卫生研究院;

关键词：

UNITED-STATES REGISTRY; VASCULAR RISK-FACTORS; VERTEBRAL ARTERY; ISCHEMIC-STROKE; FIBROMUSCULAR DYSPLASIA; ENDOVASCULAR TREATMENT; SUBARACHNOID HEMORRHAGE; CEREBELLAR ARTERY; ANEURYSMS; ANTICOAGULATION;

D O I：

10.1016/S1474-4422(15)00009-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Spontaneous intracranial artery dissection is an uncommon and probably underdiagnosed cause of stroke that is defined by the occurrence of a haematoma in the wall of an intracranial artery. Patients can present with headache, ischaemic stroke, subarachnoid haemorrhage, or symptoms associated with mass effect, mostly on the brainstem. Although intracranial artery dissection is less common than cervical artery dissection in adults of European ethnic origin, intracranial artery dissection is reportedly more common in children and in Asian populations. Risk factors and mechanisms are poorly understood, and diagnosis is challenging because characteristic imaging features can be difficult to detect in view of the small size of intracranial arteries. Therefore, multimodal follow-up imaging is often needed to confirm the diagnosis. Treatment of intracranial artery dissections is empirical in the absence of data from randomised controlled trials. Most patients with subarachnoid haemorrhage undergo surgical or endovascular treatment to prevent rebleeding, whereas patients with intracranial artery dissection and cerebral ischaemia are treated with antithrombotics. Prognosis seems worse in patients with subarachnoid haemorrhage than in those without.

引用

页码：640 / 654

页数：15

共 101 条

[1] INTRA-CRANICAL HEMORRHAGE PRODUCED BY SPONTANEOUS DISSECTING INTRA-CRANICAL ANEURYSM [J].