Viscosimetric behaviour of hyaluronic acid in different aqueous solutions

被引:39
作者
Garcia-Abuin, A. [1 ]
Gomez-Diaz, D. [1 ]
Navaza, J. M. [1 ]
Regueiro, L. [1 ]
Vidal-Tato, I. [1 ]
机构
[1] Univ Santiago Compostela, Dept Chem Engn, ETSE, E-15782 Santiago De Compostela, Galicia, Spain
关键词
Rheology; Hyaluronic acid; Apparent viscosity; Alcohol; INTRINSIC-VISCOSITY; MOLECULAR-WEIGHT; RHEOLOGY; TEMPERATURE; GUM; MIXTURES;
D O I
10.1016/j.carbpol.2011.02.028
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Rheological properties of aqueous solutions of hyaluronic acid (HA), of interest for the medical and cosmetics industry, have been studied. The value of the intrinsic viscosity of hyaluronic acid has been determined using Huggins and Kramer equations, and the value of molecular weight of this polymer has been calculated on the basis of intrinsic viscosity. The apparent viscosity value and the influence of the shear rate upon this physical property and the polymer concentration in aqueous solution have been determined. The effects caused by temperature, the concentration and nature of alcohols, as well as the electrolyte presence on the theological behaviour have been also studied. These results are expected to offer enough information to obtain the theological behaviour and to have a better understanding of HA-based mixtures for different purposes. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:500 / 505
页数:6
相关论文
共 16 条
  • [1] [Anonymous], IND GUMS
  • [2] Effects of temperature and concentration on carboxymethylcellulose with sucrose rheology
    Cancela, MA
    Alvarez, E
    Maceiras, R
    [J]. JOURNAL OF FOOD ENGINEERING, 2005, 71 (04) : 419 - 424
  • [3] Poly(trimethylene terephthalate) molecular weight and Mark-Houwink equation
    Chuah, HH
    Lin-Vien, D
    Soni, U
    [J]. POLYMER, 2001, 42 (16) : 7137 - 7139
  • [4] Unusual rheological properties of a new associative polysaccharide in salt media
    Colinet, I.
    Dulong, V.
    Hamaide, T.
    Le Cerf, D.
    Picton, L.
    [J]. CARBOHYDRATE POLYMERS, 2009, 77 (04) : 743 - 749
  • [5] SHEAR-RATE, CONCENTRATION, MOLECULAR-WEIGHT, AND TEMPERATURE VISCOSITY DEPENDENCES OF HYALURONATE, A WORMLIKE POLYELECTROLYTE
    FOUISSAC, E
    MILAS, M
    RINAUDO, M
    [J]. MACROMOLECULES, 1993, 26 (25) : 6945 - 6951
  • [6] Rheology of aqueous solutions of food additives -: Effect of concentration, temperature and blending
    Gómez-Díaz, D
    Navaza, JM
    [J]. JOURNAL OF FOOD ENGINEERING, 2003, 56 (04) : 387 - 392
  • [7] Intrinsic Viscosity and Flow Behaviour of Arabic Gum Aqueous Solutions
    Gomez-Diaz, Diego
    Navaza, Jose M.
    Quintans-Riveiro, L. C.
    [J]. INTERNATIONAL JOURNAL OF FOOD PROPERTIES, 2008, 11 (04) : 773 - 780
  • [8] Intrinsic viscosity and viscoelastic properties of xanthan/guar mixtures in dilute solutions: Effect of salt concentration on the polymer interactions
    Khouryieh, H. A.
    Herald, T. J.
    Aramouni, F.
    Alavi, S.
    [J]. FOOD RESEARCH INTERNATIONAL, 2007, 40 (07) : 883 - 893
  • [9] Intrinsic viscosities and Huggins constants of guar gum in alkali metal chloride solutions
    Ma, Xiaodong
    Pawlik, Marek
    [J]. CARBOHYDRATE POLYMERS, 2007, 70 (01) : 15 - 24
  • [10] Evaluation of radius of gyration and intrinsic viscosity molar mass dependence and stiffness of hyaluronan
    Mendichi, R
    Soltés, L
    Schieroni, AG
    [J]. BIOMACROMOLECULES, 2003, 4 (06) : 1805 - 1810