Bacterial versatility requires DEAD-box RNA helicases

被引:59
作者
Redder, Peter [1 ]
Hausmann, Stephane [1 ]
Khemici, Vanessa [1 ]
Yasrebi, Haleh [1 ]
Linder, Patrick [1 ]
机构
[1] Univ Geneva, Fac Med, CMU, Dept Microbiol & Mol Med, CH-1211 Geneva 4, Switzerland
基金
瑞士国家科学基金会;
关键词
RNA helicase; ribosome biogenesis; translation initiation; RNA turnover; bacteria; gene expression; 23S RIBOSOMAL-RNA; COLI STRAINS LACKING; VIBRIO-ANGUSTUM S14; CEREUS ATCC 14579; ESCHERICHIA-COLI; MESSENGER-RNA; BACILLUS-SUBTILIS; STAPHYLOCOCCUS-AUREUS; IN-VIVO; SACCHAROMYCES-CEREVISIAE;
D O I
10.1093/femsre/fuv011
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
RNA helicases of the DEAD-box and DEAH-box families are important players in many processes involving RNA molecules. These proteins can modify RNA secondary structures or intermolecular RNA interactions and modulate RNA-protein complexes. In bacteria, they are known to be involved in ribosome biogenesis, RNA turnover and translation initiation. They thereby play an important role in the adaptation of bacteria to changing environments and to respond to stress conditions.
引用
收藏
页码:392 / 412
页数:21
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