Located in the Qiyugou gold ore-field, the south-eastern margin of the Xiong'ershan area in the western Henan province, the Gongyu altered tectonite-type gold deposit occurs in the NE-trending fracture zones. In this paper the homogenization temperatures and salinity of the fluid inclusions as well as their He-Ar and S-H-O isotopic compositions were systematically measured based oil 13 samples from the main phase of gold mineralization. The fluid inclusions in the Gongyu mine call be divided into four types, i.e. vapor-aqueous, aqueous, CO2-bearing inclusions. The fluid inclusion bubbles are 2 -20 mu m in diameter. mostly in the range of 2 similar to 4 mu m. The homogenization temperatures of the fluid inclusions ranges from 120 degrees C similar to 440 degrees C, and dominates by 150 degrees C similar to 250 degrees C, with three distribution from 150 degrees C similar to 190 degrees C, 210 degrees C similar to 250 degrees C and 290 similar to 350 degrees C. The gold mineralization temperatures vary from 210 degrees C similar to 250 degrees C. Their ice-melting temperatures varies from -2.5 degrees C similar to -13.5 degrees C, corresponding to a ranges of salinities 4. 18 wt% similar to 13.51 wt% NaCl equivalent. The S-H-O isotopic analytical results show that delta S-34 values of sulfide are in the range of -1.7 parts per thousand - 2.2 parts per thousand and close to the value of meteorolite, indicating that the ore-forming substance was probably derived from the Upper mantle or some deep place. The delta D and the delta O-18(H2O) values of the first stage of main phase of gold mineralization are -68 parts per thousand similar to -86 parts per thousand and +3.5 parts per thousand similar to +4.9 parts per thousand respectively, implying that the ore-forming fluids were derived mainly from the deep place. The delta D and the delta O-18(H2O) values of the second stage of main phase of gold mineralization are -67 parts per thousand similar to -84 parts per thousand and -3.7 parts per thousand similar to +2.6 parts per thousand respectively, suggesting that the ore-forming fluids probably came from the deep fluid and the meteoric water. The Ar-He analytical results show that He-3/He-4 ratios of fluid inclusions in pyrite are 1.05 similar to 3.17 R/Ra, much higlier 100 times than that of the crust and lower markedly that of the mantle. Ar-40/Ar-36 ratios are 298 similar to 391, slightly higher than that of atmosphere. Ar-40 /He-4 ratios of metallogenic fluids are 0.08 similar to 0.35 with a mean of 0.20, which are consistent with the value of the crust (0.156). Helium and argon isotope composition of fluid inclusions suggest that the Source of ore-forming fluids is mainly meteoric water, and also have some mantle fluids. Therefore, the above data demonstrate that the Gongyu gold deposit is genetically related to mantle fluids. In the Qiyugou orefield, although Qiygou gold deposit (cryptoexplosive breccia type) and Gongyu gold deposit (altered tectonite-type) developed in different types, their fluid inclusions and He-Ar-S-H-O isotopic data show that they originated from the same source and deposited in the same period but at different position, and probably formed in the same metallogenic system which is related to the hydrothermal fluid of Yanshanian period in Qiyugou orefield.